Basic information Safety Supplier Related

alpha-MaleiMidopropionyl-oMega-succiniMidyl-6(ethylene glycol)

Basic information Safety Supplier Related

alpha-MaleiMidopropionyl-oMega-succiniMidyl-6(ethylene glycol) Basic information

Product Name:
alpha-MaleiMidopropionyl-oMega-succiniMidyl-6(ethylene glycol)
Synonyms:
  • alpha-MaleiMidopropionyl-oMega-succiniMidyl-6(ethylene glycol)
  • Mal-PEG6-NHS
  • α-MaleiMidopropionyl-ω-succiniMidyl-6(ethylene glycol)
  • 25-(2,5-Dihydro-2,5-dioxo-1H-pyrrol-1-yl)-23-oxo-4,7,10,13,16,19-hexaoxa-22-azapentacosanoic acid 2,5-dioxo-1-pyrrolidinyl ester
  • Mal-amido-PEG6-NHS ester
  • 3-(2-Maleimidoethylcarbonyl)amino(peg6)propionic acid N-Hydroxysuccinimide ester
  • Maleimide-PEG6-NHS ester
  • Maleimide-PEG6-succinimidyl ester
CAS:
1137109-21-7
MF:
C26H39N3O13
MW:
601.6
Product Categories:
  • peg
Mol File:
1137109-21-7.mol
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alpha-MaleiMidopropionyl-oMega-succiniMidyl-6(ethylene glycol) Chemical Properties

Melting point:
54 - 57°C
Density 
1.32±0.1 g/cm3(Predicted)
storage temp. 
-20°C
solubility 
Acetonitrile (Slightly), Water (Slightly)
pka
15.01±0.46(Predicted)
form 
Solid
color 
White to Off-White
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Safety Information

WGK Germany 
3
HS Code 
2928009090
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alpha-MaleiMidopropionyl-oMega-succiniMidyl-6(ethylene glycol) Usage And Synthesis

Description

Mal-amido-PEG6-NHS is a PEG linker containing a maleimide group and an NHS ester. The hydrophilic PEG spacer increases solubility in aqueous media. The NHS ester can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules. The maleimide group will react with a thiol group to form a covalent bond, enabling the connection of biomolecule with a thiol.

Uses

Heterobifunctional crosslinker with an ethylene oxide spacer for linking amine- to sulfhydryl-containing compounds or biomolecules. Maleimide functional group will react with sulfhydryls and the succinimidyl ester group will react with amines. Spacer length is 31.7 angstroms.

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