2-Bromobenzyl bromide Chemical Properties

Melting point:

29-32 °C (lit.)

Boiling point:

129 °C/19 mmHg (lit.)

Density 

1.8246 (rough estimate)

refractive index 

n20/D 1.619(lit.)

Flash point:

>230 °F

storage temp. 

Inert atmosphere,Room Temperature

solubility 

dioxane: soluble1g/10 mL, clear, colorless

form 

Liquid After Melting

color 

Clear colorless to yellow

Water Solubility 

Insoluble in water.

BRN 

971015

InChI

InChI=1S/C7H6Br2/c8-5-6-3-1-2-4-7(6)9/h1-4H,5H2

InChIKey

LZSYGJNFCREHMD-UHFFFAOYSA-N

SMILES

C1(Br)=CC=CC=C1CBr

CAS DataBase Reference

3433-80-5(CAS DataBase Reference)

NIST Chemistry Reference

Benzene, 1-bromo-2-(bromomethyl)-(3433-80-5)

EPA Substance Registry System

2-Bromobenzyl bromide (3433-80-5)

Safety Information

Hazard Codes 

C,T

Risk Statements 

34-37-23

Safety Statements 

26-36/37/39-45-22

RIDADR 

UN 3261 8/PG 3

WGK Germany 

3

F 

8-19

TSCA 

TSCA listed

HazardClass 

8

PackingGroup 

III

HS Code 

29036990

Storage Class

8A - Combustible corrosive hazardous materials

Hazard Classifications

Eye Dam. 1
Skin Corr. 1B

MSDS

• Language:English Provider:alpha,o-Dibromotoluene
• Language:English Provider:ACROS
• Language:English Provider:SigmaAldrich
• Language:English Provider:ALFA

2-Bromobenzyl bromide Usage And Synthesis

Chemical Properties

clear colorless to yellowish liquid after melting

Uses

2-Bromobenzyl bromide was used in the synthesis of substituted quinazolines and 1,2,3,4-tetrahydroquinazolines, 2- and 3-substituted indenes, tris-2-bromotribenzylamine3.

Uses

2-Bromobenzyl bromide was used in the synthesis of:

• substituted quinazolines and 1,2,3,4-tetrahydroquinazolines
• 2- and 3-substituted indenes
• tris-2-bromotribenzylamine

Synthesis

In the reaction flask, 15g of toluene was added to 100mL of glacial acetic acid, and then 3g of iron powder was added to the localization catalyst, and 8mL of bromine was slowly added dropwise under the condition of room temperature for about 30min, and then the reaction was carried out at 40?? for 5h, and then put into a tungsten lamp at 300W for 5h, and then the reaction was completely monitored by TLC, and the solvent glacial acetic acid was evaporated under vacuum, and a certain amount of concentrate was added to it. A certain amount of sodium hydroxide solution with a mass concentration of 20% was added to the concentrate, the reaction solution was filtered, the filtrate was extracted with dichloromethane for three times, and the organic phases were combined, and the organic phase was then dried with anhydrous sodium sulfate and concentrated to obtain 24g of o-bromobenzyl bromide; 1HNMR (400MHz, CDCl3) ??: 7.51 (d, J=12.0Hz, 1H), 7.27-7.23 (m, 3H), 4.37 (s). ,2H).

2-Bromobenzyl bromide(3433-80-5)Related Product Information

• alpha-Chloro-o-fluorotoluene
• Allyl bromide
• 2-(Chloromethyl)benzonitrile
• Ethidium bromide
• Diethylstilbestrol
• 2-Chlorobenzyl chloride
• Rocuronium bromide
• 2-(Trifluoromethyl)benzyl chloride
• 2-Bromophenol
• Sodium bromate
• Benzyl bromide
• 2-Bromobenzonitrile
• 2-Bromobenzyl cyanide
• 5-FLUORO-2-BROMOBENZYL BROMIDE
• 2-BROMO-5-METHOXYBENZYL BROMIDE 97
• 1-BROMO-2-(BROMOMETHYL)NAPHTHALENE
• 2-fluor-4-bromobenzyl bromide,2-FLUORO-4-BROMOBENZYL BROMIDE
• Methyl bromide