Trifluoromethylthiobenzene Chemical Properties

Boiling point:

142 °C (lit.)

Density 

1.249 g/mL at 25 °C (lit.)

refractive index 

n20/D 1.466(lit.)

Flash point:

100 °F

form 

clear liquid

color 

Colorless to Almost colorless

Sensitive 

Stench

BRN 

2043134

CAS DataBase Reference

456-56-4(CAS DataBase Reference)

NIST Chemistry Reference

Phenyl trifluoromethyl sulfide(456-56-4)

Safety Information

Hazard Codes 

T

Risk Statements 

10-36/37/38

Safety Statements 

16-36-36/37/39-23

RIDADR 

UN 1993 3/PG 3

WGK Germany 

3

Hazard Note 

Toxic/Stench

HazardClass 

3

PackingGroup 

III

HS Code 

29309090

MSDS

• Language:English Provider:Phenyl trifluoromethyl sulfide
• Language:English Provider:SigmaAldrich
• Language:English Provider:ALFA

Trifluoromethylthiobenzene Usage And Synthesis

Uses

Phenyl trifluoromethyl sulfide may be used in the preparation of:

• sulfoxides, dithiane dioxide, and dithiolane dioxide via iron-catalyzed oxidation of sulfides, dithiane, or dithiolane with hydrogen peroxide
• benzophenone hydrazone derivatives
• trifluoro- and difluoromethylsilanes by reductive coupling of fluoromethyl sulfones, sulfoxides and sulfides with chlorosilanes

Synthesis Reference(s)

The Journal of Organic Chemistry, 50, p. 4047, 1985 DOI: 10.1021/jo00221a017
Synthesis, p. 721, 1975 DOI: 10.1055/s-1975-23905

General Description

Phenyl trifluoromethyl sulfide (PTFMS) is an aryl trifluoromethyl sulfide. PTFMS with (triethylgermyl)sodium forms a reagent system that has been employed for the trifluoromethylation of certain imines. The reaction between OH radical and PTFMS has been analyzed using pulse radiolysis technique and quantum chemical calculations.

Trifluoromethylthiobenzene(456-56-4)Related Product Information

• Sodium sulfide
• Benzotrifluoride
• 2-(Trifluoromethyl)benzaldehyde
• 3-(Trifluoromethyl)benzaldehyde
• 4'-(Trifluoromethyl)acetophenone
• Hydrogen Sulfide
• tert-Butyl methyl ether
• 2-(Trifluoromethyl)benzoic acid
• Diphenyl sulfide
• Dimethyl sulfide
• PHENYL VALERATE
• CARBONYL SULFIDE
• Trityl candesartan cilexetil
• Tributyrin
• PHENYL RESIN
• 4-(Trifluoromethylthio)nitrobenzene
• 4-(TRIFLUOROMETHYLTHIO)BROMOBENZENE
• 4-(TRIFLUOROMETHYLTHIO)BENZALDEHYDE