DEA NONOate Chemical Properties

storage temp. 

-70°C

solubility 

Soluble in Water or Ethanol

form 

White to off-white solid.

color 

Off-white

Stability:

Stable for 1 year from date of purchase s supplied. Protect from exposure to air or moisture. Solutions are not stable and must be prepared immediately before use. See the product description for information on half-life in solution.

Safety Information

Hazard Codes 

Xn

Risk Statements 

22-37/38-41

Safety Statements 

26-39

WGK Germany 

3

DEA NONOate Usage And Synthesis

Description

DEA NONOate is a NO donor. It spontaneously dissociates in a pH-dependent, first-order process with a half-life of 2 minutes and 16 minutes at 37°C and 22-25°C, pH 7.4, respectively, to liberate 1.5 moles of NO per mole of parent compound.

Chemical Properties

White Solid

Uses

A reagent which releases Nitric Oxide into aqueous solutions at controlled rates for in vitro studies.

Uses

Used as:

• Reagent for reductive nitrosylation of Wilkinson′s catalyst
• Nitric oxide (NO) donor

Definition

ChEBI: Diethylamine NONOate is an organoammonium salt that is the diethylammonium salt of 1,1-diethyl-2-hydroxy-3-oxotriazane. It has a role as a nitric oxide donor. It contains a NONOate(1-).

Biochem/physiol Actions

NO donor

References

1) Keefer?et al. (1996),?“NONOates” (1-substituted diazen-1-ium-1,2-diolates) as nitric oxide donors: Convenient nitric oxide dosage forms; Methods Enzymol.,?268?281

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