Basic information Safety Supplier Related

1-(2-chloro-4-hydroxyphenyl)-3-cyclopropylurea

Basic information Safety Supplier Related

1-(2-chloro-4-hydroxyphenyl)-3-cyclopropylurea Basic information

Product Name:
1-(2-chloro-4-hydroxyphenyl)-3-cyclopropylurea
Synonyms:
  • 1-(2-chloro-4-hydroxyphenyl)-3-cyclopropylurea
  • N-(2-chloro-4-hydroxyphenyl)-N'-cyclopropyl-Urea
  • Urea, N-(2-chloro-4-hydroxyphenyl)-N'-cyclopropyl-
  • Lenvatinib Impurity a
  • lenvaint-I
  • (Z)-N-(2-chloro-4-hydroxyphenyl)-N-cyclopropylcarbamimidic acid
  • Lenvatinib Impurity LFS-A
  • (2-Chloro-4-hydroxyphenyl)-N'-cyclopropyl- urea
CAS:
796848-79-8
MF:
C10H11ClN2O2
MW:
226.66
Mol File:
796848-79-8.mol
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1-(2-chloro-4-hydroxyphenyl)-3-cyclopropylurea Chemical Properties

Boiling point:
364.6±42.0 °C(Predicted)
Density 
1.43±0.1 g/cm3(Predicted)
storage temp. 
2-8°C
solubility 
DMSO (Slightly), Methanol (Slightly)
pka
9.37±0.31(Predicted)
form 
Solid
color 
Off-White to Light Beige
InChI
InChI=1S/C10H11ClN2O2/c11-8-5-7(14)3-4-9(8)13-10(15)12-6-1-2-6/h3-6,14H,1-2H2,(H2,12,13,15)
InChIKey
QVPZNUIZEVRITP-UHFFFAOYSA-N
SMILES
N(C1=CC=C(O)C=C1Cl)C(NC1CC1)=O
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1-(2-chloro-4-hydroxyphenyl)-3-cyclopropylurea Usage And Synthesis

Uses

Desquinolinyl Lenvatinib is a metabolite of Lenvatinib (L329400) which is an orally active inhibitor of multiple receptor tyrosine kinases including VEGF, FGF and SCF receptors.

1-(2-chloro-4-hydroxyphenyl)-3-cyclopropylureaSupplier

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