2,4,6-TRIBROMO-3,5-DIFLUOROPYRIDINE Chemical Properties

Melting point:

108-110°C

Boiling point:

251.5±35.0 °C(Predicted)

Density 

2.519±0.06 g/cm3(Predicted)

pka

-5.26±0.10(Predicted)

CAS DataBase Reference

30841-93-1(CAS DataBase Reference)

Safety Information

Hazard Codes 

Xi

Risk Statements 

20/21/22-36/37/38

Safety Statements 

26-36/37/39

Hazard Note 

Irritant

HS Code 

2933399990

2,4,6-TRIBROMO-3,5-DIFLUOROPYRIDINE Usage And Synthesis

Synthesis

Combination of HBr and AlBr3 would be expected to give a super-acid (H+ AIBq-) and we might anticipate that this would provide a very powerful brominating agent. Indeed it has been shown that tetrafluoropyrazine (which is less basic than pentafluoropyridine) gives tetrabromopyrazine on treatment with H+ AlBr4-, therefore, we expected that H+ AIBq- would react well with (3). This proved to be the case and reaction of pentafluoropyridine with H+ AIBq- gave 2,4,6-tribromo-3,5-difluoropyridine as a single product in high yield.

2,4,6-TRIBROMO-3,5-DIFLUOROPYRIDINE(30841-93-1)Related Product Information

• 3,5-Difluoropyridine
• 2-Bromo-3,5-dichloropyridine
• 2,4,6-TRIBROMO-3,5-DIFLUOROPYRIDINE
• 2,4-Dibromopyridine
• 2,4,6-Tribromopyridine
• 3-Fluoro-4-bromopyridine
• 2-Bromo-3-fluoropyridine
• 2-Bromo-5-fluoropyridine