2-Chloro-4-amino-6,7-dimethoxyquinazoline Chemical Properties

Melting point:

262-268 °C (dec.)(lit.)

Boiling point:

374.0±42.0 °C(Predicted)

Density 

1.5062 (rough estimate)

vapor pressure 

0Pa at 25℃

refractive index 

1.5500 (estimate)

storage temp. 

2-8°C

solubility 

DMSO (Sparingly, Heated), Methanol (Slightly, Heated)

pka

4.35±0.30(Predicted)

color 

White to Off-White

Water Solubility 

1.418g/L at 25℃

BRN 

747463

LogP

1.5 at 25℃

CAS DataBase Reference

23680-84-4(CAS DataBase Reference)

NIST Chemistry Reference

4-Amino-2-chloro-6,7-dimethoxyquinazoline(23680-84-4)

Safety Information

Hazard Codes 

Xi,Xn

Risk Statements 

36/37/38-20/21/22

Safety Statements 

26-36-37/39

WGK Germany 

3

F 

10

HazardClass 

IRRITANT

HS Code 

29339900

MSDS

• Language:English Provider:2-Chloro-4-amino-6,7-dimethoxyquinazoline
• Language:English Provider:ACROS
• Language:English Provider:SigmaAldrich
• Language:English Provider:ALFA

2-Chloro-4-amino-6,7-dimethoxyquinazoline Usage And Synthesis

Chemical Properties

Off-White Solid

Uses

Intermediate in the production on Terazosin.

Synthesis Reference(s)

Journal of Medicinal Chemistry, 20, p. 146, 1977 DOI: 10.1021/jm00211a031

Flammability and Explosibility

Non flammable

2-Chloro-4-amino-6,7-dimethoxyquinazoline(23680-84-4)Related Product Information

• 4-Dimethylaminobenzoic acid
• 6-Aminocaproic acid
• ALTRENOGEST
• Glycine
• Tris(hydroxymethyl)aminomethane
• 3-Aminophenol
• Triethanolamine
• Dimethyldimethoxysilane
• 4-Dimethylaminopyridine
• 4-Dimethylaminobenzaldehyde
• Triallylamine
• Dibenzylamine
• Bis(2-ethylhexyl)amine
• Terazosin impurity
• 2-Piperazine-4-amino-6,7-dimethoxyquinazoline
• (R)-Terazosin
• 2,2'-(1,4-Piperazinediyl)bis[6,7-diMethoxy-4-quinazolinaMine]
• 1-[4-(4-AMino-6,7-diMethoxy-2-quinazolinyl)-1-piperazinyl]-5-hydroxy-1-pentanone