Basic information Safety Supplier Related

2-(Benzyloxyethoxyethoxy)ethylaMine

Basic information Safety Supplier Related

2-(Benzyloxyethoxyethoxy)ethylaMine Basic information

Product Name:
2-(Benzyloxyethoxyethoxy)ethylaMine
Synonyms:
  • 2-(Benzyloxyethoxyethoxy)ethylaMine
  • 2-(2-(2-(benzyloxy)ethoxy)ethoxy)ethanamine
  • Benzyl-PEG3-amine
  • BnO-PEG2-CH2CH2NH2
  • CAS_86770-75-4
  • Benzyl-PEG3-NH2
  • 2-[2-(2-Benzyloxy-ethoxy)-ethoxy
  • H2N-(CH2CH2O)3-Bn
CAS:
86770-75-4
MF:
C13H21NO3
MW:
239.31
Mol File:
86770-75-4.mol
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2-(Benzyloxyethoxyethoxy)ethylaMine Chemical Properties

Boiling point:
348.7±27.0 °C(Predicted)
Density 
1.051±0.06 g/cm3(Predicted)
pka
8.74±0.10(Predicted)
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2-(Benzyloxyethoxyethoxy)ethylaMine Usage And Synthesis

Biological Activity

Benzyl-PEG3-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

References

[1]. Nalawansha DA, et al. PROTACs: An Emerging Therapeutic Modality in Precision Medicine. Cell Chem Biol. 2020;27(8):998-985.

2-(Benzyloxyethoxyethoxy)ethylaMineSupplier

9ding chemical ( Shanghai) Limited
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