CY7-Sulfo NHS Ester
CY7-Sulfo NHS Ester Basic information
- Product Name:
- CY7-Sulfo NHS Ester
- Synonyms:
-
- Cy7-SE
- Sulfo-Cy7-SE
- Cy7 dye
- Sulfo-Cy7-SE, >95%
- 2-[7-[1-[6-[(2,5-Dioxo-1-pyrrolidinyl)oxy]-6-oxohexyl]-1,3-dihydro-3,3-dimethyl-5-sulfo-2H-indol-2-ylidene]-1,3,5-heptatrien-1-yl]-1-ethyl-3,3-dimethyl-5-sulfo-3H-indolium, inner salt
- Sulfo-Cyanine7 Succinimidyl Ester
- sulfo-cyanine7,Cy7-SE
- diSulfo-Cy7 NHS ester(Ethyl)
- CAS:
- 477908-53-5
- MF:
- C39H45N3O10S2
- MW:
- 779.92
- Product Categories:
-
- cy
- Mol File:
- 477908-53-5.mol
CY7-Sulfo NHS Ester Chemical Properties
- storage temp.
- under inert gas (nitrogen or Argon) at 2–8 °C
- solubility
- DMF: soluble; DMSO: soluble; Ethanol: soluble
- form
- A crystalline solid
- color
- Light brown to black
- Appearance
- Dark green solid
- ex/em
- 748/774 nm
- ε(extinction coefficient)
- 200,000 L⋅mol−1⋅cm−1
- Φ(quantum yield)
- 0.24
- InChIKey
- ROGODJHHEBREAB-UHFFFAOYSA-N
- SMILES
- C(N1C(C(C)(C)C2=CC(S(O)(=O)=O)=CC=C12)=CC=CC=CC=CC1C(C2=CC(S([O-])(=O)=O)=CC=C2[N+]=1CC)(C)C)CCCCC(=O)ON1C(CCC1=O)=O
CY7-Sulfo NHS Ester Usage And Synthesis
Description
Cy7-NHS ester is a near IR dye.
Chemical Properties
Appearance: Dark green solid
ex/em: 748/774 nm
Extinction coefficient (ε): 200,000 L??mol??1??cm??1
Quantum yield (Φ): 0.24
Uses
CY7-SE is a CY dye. CY, short for Cyanine, is a compound consisting of two nitrogen atoms connected by an odd number of methyl units. Cyanine compounds have the characteristics of long wavelength, adjustable absorption and emission, high extinction coefficient, good water solubility and relatively simple synthesis[1]. CY dyes are of en used for the labeling of proteins, antibodies and small molecular compounds. For the labeling of protein antibodies, the combination can be completed through a simple mixing reaction. Below, we introduce the labeling method of protein antibody labeling, which has certain reference significance[2].
Definition
ChEBI: A C7-cyanine dye having differentially-substituted 2-indolyl units at each end.
References
[1] Ptaszek M. Rational design of fluorophores for in vivo applications. Prog Mol Biol Transl Sci. 2013;113:59-108. DOI:10.1016/B978-0-12-386932-6.00003-X
[2] Shindy, H. A. (2017). Fundamentals in the chemistry of cyanine dyes: A review. Dyes and Pigments, 145, 505–513. doi:10.1016/j.dyepig.2017.06.029
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