Basic information Safety Supplier Related

CY7-Sulfo NHS Ester

Basic information Safety Supplier Related

CY7-Sulfo NHS Ester Basic information

Product Name:
CY7-Sulfo NHS Ester
Synonyms:
  • Cy7-SE
  • Sulfo-Cy7-SE
  • Cy7 dye
  • Sulfo-Cy7-SE, >95%
  • 2-[7-[1-[6-[(2,5-Dioxo-1-pyrrolidinyl)oxy]-6-oxohexyl]-1,3-dihydro-3,3-dimethyl-5-sulfo-2H-indol-2-ylidene]-1,3,5-heptatrien-1-yl]-1-ethyl-3,3-dimethyl-5-sulfo-3H-indolium, inner salt
  • Sulfo-Cyanine7 Succinimidyl Ester
  • sulfo-cyanine7,Cy7-SE
  • diSulfo-Cy7 NHS ester(Ethyl)
CAS:
477908-53-5
MF:
C39H45N3O10S2
MW:
779.92
Product Categories:
  • cy
Mol File:
477908-53-5.mol
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CY7-Sulfo NHS Ester Chemical Properties

storage temp. 
under inert gas (nitrogen or Argon) at 2–8 °C
solubility 
DMF: soluble; DMSO: soluble; Ethanol: soluble
form 
A crystalline solid
color 
Light brown to black
Appearance
Dark green solid
ex/em
748/774 nm
ε(extinction coefficient)
200,000 L⋅mol−1⋅cm−1
Φ(quantum yield)
0.24
InChIKey
ROGODJHHEBREAB-UHFFFAOYSA-N
SMILES
C(N1C(C(C)(C)C2=CC(S(O)(=O)=O)=CC=C12)=CC=CC=CC=CC1C(C2=CC(S([O-])(=O)=O)=CC=C2[N+]=1CC)(C)C)CCCCC(=O)ON1C(CCC1=O)=O
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Safety Information

HS Code 
32049010
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CY7-Sulfo NHS Ester Usage And Synthesis

Description

Cy7-NHS ester is a near IR dye.

Chemical Properties

Appearance: Dark green solid
ex/em: 748/774 nm
Extinction coefficient (ε): 200,000 L??mol??1??cm??1
Quantum yield (Φ): 0.24

Uses

CY7-SE is a CY dye. CY, short for Cyanine, is a compound consisting of two nitrogen atoms connected by an odd number of methyl units. Cyanine compounds have the characteristics of long wavelength, adjustable absorption and emission, high extinction coefficient, good water solubility and relatively simple synthesis[1]. CY dyes are of en used for the labeling of proteins, antibodies and small molecular compounds. For the labeling of protein antibodies, the combination can be completed through a simple mixing reaction. Below, we introduce the labeling method of protein antibody labeling, which has certain reference significance[2].

Definition

ChEBI: A C7-cyanine dye having differentially-substituted 2-indolyl units at each end.

References

[1] Ptaszek M. Rational design of fluorophores for in vivo applications. Prog Mol Biol Transl Sci. 2013;113:59-108. DOI:10.1016/B978-0-12-386932-6.00003-X
[2] Shindy, H. A. (2017). Fundamentals in the chemistry of cyanine dyes: A review. Dyes and Pigments, 145, 505–513. doi:10.1016/j.dyepig.2017.06.029

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