Kushenol X Chemical Properties

solubility 

Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.

form 

Cryst.

color 

White to off-white

Kushenol X Usage And Synthesis

Uses

Kushenol X, a flavonoid compound isolated from the roots of Sophora flavescens. Kushenol X is a potent β-glucuronidase and human carboxylesterase 2 (hCE2) inhibitor with IC50s of 2.07 μM and 3.05 μM, respectively[1][2].

References

[1] Cheng-Peng Sun, et al. The study of inhibitory effect of natural flavonoids toward β-glucuronidase and interaction of flavonoids with β-glucuronidase. Int J Biol Macromol. 2020 Jan 15;143:349-358. DOI:10.1016/j.ijbiomac.2019.12.057
[2] Sha-Sha Song, et al. Flavonoids as human carboxylesterase 2 inhibitors: Inhibition potentials and molecular docking simulations. Int J Biol Macromol. 2019 Jun 15;131:201-208. DOI:10.1016/j.ijbiomac.2019.03.060

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