5-(2-fluorophenyl)-1H-pyrrole-3-carbonitrile Chemical Properties

Boiling point:

364.7±32.0 °C(Predicted)

Density 

1.28±0.1 g/cm3(Predicted)

storage temp. 

Sealed in dry,Room Temperature

pka

13.87±0.50(Predicted)

form 

Solid

Dielectric constant

5.5（22.0℃）

InChI

InChI=1S/C11H7FN2/c12-10-4-2-1-3-9(10)11-5-8(6-13)7-14-11/h1-5,7,14H

InChIKey

ZDEFHFJZEDEKJO-UHFFFAOYSA-N

SMILES

N1C(C2=CC=CC=C2F)=CC(C#N)=C1

Safety Information

HS Code 

2933998090

5-(2-fluorophenyl)-1H-pyrrole-3-carbonitrile Usage And Synthesis

Description

5-(2-fluorophenyl)-1H-pyrrole-3-carbonitrile is an important pharmaceutical intermediate component for the preparation of vonorasan fumarate, vonoprazan key intermediate, and vorexanol fumarate intermediate.

Uses

5-(2-Fluorophenyl)-1H-pyrrole-3-carbonitrile is an impurity of Vonoprazan (V767010) a novel potassium-competitive acid blocker for the treatment of acid-related diseases.

5-(2-fluorophenyl)-1H-pyrrole-3-carbonitrile(1240948-77-9)Related Product Information

• 2-chloro-5-(2-fluorophenyl)-1H-pyrrole-3-carbonitrile
• 3-Pyridinesulfonic acid
• 2-[2-(2-Fluorophenyl)-2-oxoethyl]propanedinitrile
• 5-(2-Fluorophenyl)-1H-pyrrole-3-carbaldehyde
• 3-N,N-dimethylsulfamoylpyridine
• (5-(2-fluorophenyl)-1-(pyridin-3-ylsulfonyl)-1H-pyrrol-3-yl) methanol
• 1H-Pyrrole-3-carboxylic acid, 5-(2-fluorophenyl)-, ethyl ester
• 5-(4-fluorophenyl)-1H-pyrrole-3-carbonitrile
• 1H-PYRROLE-3-METHANOL, 5-(2-FLUOROPHENYL)-
• PYRIDINE-2-SULFONIC ACID
• 1-(5-(2-fluorophenyl)-1-(pyridin-2-ylsulfonyl)-1H-pyrrol-3-yl)-N- methylmethanamine fumarate
• (Z)-N-((5-(2-fluorophenyl)-1-(pyridin-3-ylsulfonyl)-1H-pyrrol-3-yl)methylene)methanamine oxide
• 1-methylpyridin-1-ium-4-sulfonate
• 4-Pyridinesulphonic acid
• pyridine-3-sulfonyl chloride
• 1H-Pyrrole-3-carbonitrile,5-(2-fluorophenyl)-1-(3-pyridinylsulfonyl)-
• 5-(2-Fluorophenyl)-1-(pyridin-3-ylsulfonyl)-1H-pyrrole-3-carbaldehyde
• 5-chloropyridine-3-sulfonyl chloride