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Dasatinib iMpurity

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Dasatinib iMpurity Basic information

Product Name:
Dasatinib iMpurity
Synonyms:
  • Dasatinib Hydrate IMP
  • CL090
  • Dasatinib Imp.
  • Dasatinib Deschloro Impurity
  • Deschlorodasatinib
  • 2-[[6-[4-(2-Hydroxyethyl)-1-piperazinyl]-2-methyl-4-pyrimidinyl]amino]-N-(2-methylphenyl)-5-thiazolecarboxamide
  • dasatinib Deschloro IMP
  • Dasatinib impurity 5/Deschloro Dasatinib/2-[[6-[4-(2-Hydroxyethyl)-1-piperazinyl]-2-methyl-4-pyrimidinyl]amino]-N-(2-methylphenyl)-5-thiazolecarboxamide
CAS:
1184919-23-0
MF:
C22H27N7O2S
MW:
453.56
Product Categories:
  • Metabolites & Impurities, Pharmaceuticals, Intermediates & Fine Chemicals, Tyrosine Kinase Inhibitors
Mol File:
1184919-23-0.mol
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Dasatinib iMpurity Chemical Properties

Melting point:
>177°C (dec.)
Density 
1.356±0.06 g/cm3(Predicted)
storage temp. 
-20°C Freezer, Under inert atmosphere
solubility 
DMSO (Slightly), Ethanol (Slightly)
pka
11.87±0.70(Predicted)
form 
Solid
color 
Brown
Stability:
Stable under recommended storage conditions., Stable Under Recommended Storage C
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Dasatinib iMpurity Usage And Synthesis

Uses

Deschloro-dasatinib, is the impurity of Dasatinib (D193600), which is a new, oral, small-molecule Tyrosine Kinase Inhibitor (TKI) for the treatment of CML. It is also an Antineoplastic. It is a COVID19-related research product.

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