N-[4-Chloro-3-(trifluoromethyl)phenyl]-N'-(4-hydroxyphenyl)urea CAS#: 1129683-83-5

N-[4-Chloro-3-(trifluoromethyl)phenyl]-N'-(4-hydroxyphenyl)urea Basic information

Product Name:

N-[4-Chloro-3-(trifluoromethyl)phenyl]-N'-(4-hydroxyphenyl)urea

Synonyms:

Sorafenib related coMpound 4
1-(4-chloro-3-(trifluromethyl)phenyl)-3-(4-hydroxyphenyl)urea
Sorafenib impurity 17/1-(4-chloro-3-(trifluoromethyl)phenyl)-3-(4-hydroxyphenyl)urea
N-[4-Chloro-3-(trifluoromethyl)phenyl]-N'-(4-hydroxyphenyl)urea
Sorafenib Impurity 65
Sorafenib impurities166
Sorafenib impurities5
Urea, N-[4-chloro-3-(trifluoromethyl)phenyl]-N'-(4-hydroxyphenyl)-

CAS:

1129683-83-5

MF:

C14H10ClF3N2O2

MW:

330.69

Mol File:

1129683-83-5.mol

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N-[4-Chloro-3-(trifluoromethyl)phenyl]-N'-(4-hydroxyphenyl)urea Chemical Properties

Boiling point:: 350.1±42.0 °C(Predicted)
Density: 1.547±0.06 g/cm3(Predicted)
solubility: DMSO (Slightly), Methanol (Slightly)
form: Solid
pka: 10.16±0.26(Predicted)
color: White to Light Yellow

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N-[4-Chloro-3-(trifluoromethyl)phenyl]-N'-(4-hydroxyphenyl)urea Usage And Synthesis

Uses

1-(4-Chloro-3-trifluoromethylphenyl)-3-(4-hydroxyphenyl)urea is an impurity of Sorafenib (S676850), a kinase inhibitor targeting both RAF kinase and receptor tyrosine kinases that promote angiogensis.

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