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ChemicalBook >  Product Catalog >  Organic Chemistry >  Alcohols,Phenols,Phenol alcohols >  1,2-distearoyl-sn-glycero-3-phospho-(1'-rac-glycerol) (sodiuM salt)

1,2-distearoyl-sn-glycero-3-phospho-(1'-rac-glycerol) (sodiuM salt)

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1,2-distearoyl-sn-glycero-3-phospho-(1'-rac-glycerol) (sodiuM salt) Basic information

Product Name:
1,2-distearoyl-sn-glycero-3-phospho-(1'-rac-glycerol) (sodiuM salt)
Synonyms:
  • 1,2-distearoyl-sn-glycero-3-phospho-(1'-rac-glycerol) (sodiuM salt)
  • 1,2-Dioctadecanoyl-sn-glycero-3-phospho-(1′-rac-glycerol) sodium salt
  • L-α-Phosphatidyl-DL-glycerol, distearoyl
  • Octadecanoic acid (1R)-1-[[[(2,3-dihydroxypropoxy)hydroxyphosphinyl]oxy]methyl]-1,2-ethanediyl ester monosodium salt
  • 1,2-Distearoyl-sn-glycero-3-PG (sodium salt)
  • 1,2-DISTEAROYL-SN-GLYCERO-3-PHOSPHO-(1'-RAC-GLYCEROL) (SODIUM SALT);18:0 PG;DSPG;PG(18:0/18:0)
  • 18:0 PG
  • 1,2-Dioctadecanoyl-sn-glycero-3-phospho-(1′-rac-glycerol) sodium salt, 1,2-Distearoyl-sn-glycero-3-phosphoglycerol, L -α-Phosphatidyl-DL-glycerol, distearoyl, DSPG-Na, Octadecanoic acid (1R)-1-[[[(2,3-dihydroxypropoxy)hydroxyphosphinyl]oxy]methyl]-1,2-eth
CAS:
200880-42-8
MF:
C81H159Na2O16P
MW:
1466.072861
Mol File:
200880-42-8.mol
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1,2-distearoyl-sn-glycero-3-phospho-(1'-rac-glycerol) (sodiuM salt) Chemical Properties

storage temp. 
-20°C
solubility 
Chloroform:Methanol:Water = 2:1:0.1 (Very Slightly)
form 
Solid
color 
White to Off-White
Stability:
Hygroscopic
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Safety Information

WGK Germany 
3
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1,2-distearoyl-sn-glycero-3-phospho-(1'-rac-glycerol) (sodiuM salt) Usage And Synthesis

Description

DSPG, also known as 1,2-Distearoyl-sn-glycero-3-phosphoglycerol, is a phospholipid molecule with phosphate polar head connected to two non-polar lipid (stearic acid) by a glycerol molecule. In water, the molecule can orient itself into lipid bilayer and can be used for drug encapsulation, such as drug loaded liposomes or nanoparticles.

Uses

1,2-Distearoyl-sn-glycero-3-phospho-rac-(1-glycerol) Sodium Salt is used to prepare polyethyleneglycol-modified liposomal doxorubicin for therapies against drug resistant tumors. It is also used in the PEGylated liposomal drug formulation of the anti-cancer agent oxaliplatin.

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