MPEG16-NH2 Chemical Properties

Boiling point:

699.1±50.0 °C(Predicted)

Density 

1.084±0.06 g/cm3(Predicted)

pka

8.74±0.10(Predicted)

MPEG16-NH2 Usage And Synthesis

Biological Activity

m-PEG16-NH2 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

MPEG16-NH2(907577-50-8)Related Product Information

• alpha, oMega-Dipropionic acid hexaethylene glycol
• H2N-PEG24-tBu
• 2-(2-Methoxyethoxy)ethanamine
• OCTAETHYLENE GLYCOL
• O-(2-AMINOETHYL)-O-(2-(BOC-AMINO)ETHYL)OCTAETHYLENE GLYCOL
• 2-[2-[2-[2-[2-[2-(BENZYLOXY)ETHOXY]ETHOXY]ETHOXY]ETHOXY]ETHOXY]ETHANOL
• FMOC-21-AMINO-4,7,10,13,16,19-HEXAOXAHENEICOSANOIC ACID
• Nonaethylene glycol
• 3,6,9,12,15,18-Hexaoxanonadecane-1-thiol
• alpha, oMega-Dipropionic acid triethylene glycol
• PENTAETHYLENE GLYCOL MONOMETHYL ETHER
• MPEG3-NHS
• DODECAETHYLENE GLYCOL
• 2,5,8,11,14,17,20,23,26-Nonaoxaoctacosane-28-thiol
• HS-PEG8-CH2CH2COOH
• alpha-aMine-oMega-propionic acid hexaethylene glycol
• Amino-PEG2-acid
• MPEG6-CH2CH2COOH