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2-Azabicyclo[3.1.0]hexane-3-carbonitrile, 2-[(2S)-2-aMino-2-(3-hydroxytricyclo[3.3.1.13,7]dec-1-yl)acetyl]-, (1S,3R,5S)-

Basic information Safety Supplier Related

2-Azabicyclo[3.1.0]hexane-3-carbonitrile, 2-[(2S)-2-aMino-2-(3-hydroxytricyclo[3.3.1.13,7]dec-1-yl)acetyl]-, (1S,3R,5S)- Basic information

Product Name:
2-Azabicyclo[3.1.0]hexane-3-carbonitrile, 2-[(2S)-2-aMino-2-(3-hydroxytricyclo[3.3.1.13,7]dec-1-yl)acetyl]-, (1S,3R,5S)-
Synonyms:
  • (S,R,S,S)-Saxagliptin HCl
  • 2-Azabicyclo[3.1.0]hexane-3-carbonitrile, 2-[(2S)-2-aMino-2-(3-hydroxytricyclo[3.3.1.13,7]dec-1-yl)acetyl]-, (1S,3R,5S)-
  • Saxagliptin (S,R,S,S)-Isomer
  • (1S,3R,5S)-2-[(2S)-2-amino-2-(3-hydroxy-1-adamantyl)acetyl]-2-azabicyclo[3.1.0]hexane-3-carbonitrile
  • Saxagliptin Impurity 4(S,R,S,S-Isomer)
  • (2’S,2R,trans)-Saxagliptin
  • Saxagliptin Impurity 4 Hydrochloride (S,R,S,S-Isomer Hydrochloride)
  • SaxagliptinS,R,S,S-Isomer Hydrochloride
CAS:
1564266-00-7
MF:
C18H25N3O2
MW:
315.41
Mol File:
1564266-00-7.mol
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2-Azabicyclo[3.1.0]hexane-3-carbonitrile, 2-[(2S)-2-aMino-2-(3-hydroxytricyclo[3.3.1.13,7]dec-1-yl)acetyl]-, (1S,3R,5S)- Chemical Properties

Boiling point:
548.7±35.0 °C(Predicted)
Density 
1.35±0.1 g/cm3(Predicted)
pka
15.12±0.40(Predicted)
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2-Azabicyclo[3.1.0]hexane-3-carbonitrile, 2-[(2S)-2-aMino-2-(3-hydroxytricyclo[3.3.1.13,7]dec-1-yl)acetyl]-, (1S,3R,5S)- Usage And Synthesis

Uses

(2’S,2R,trans)-Saxagliptin is an impurity of Saxagliptin (S143500); a potent and selective reversible inhibitor of dipeptidyl peptidase-4 (DPP-IV) developed for the treatment of type 2 diabetes.

2-Azabicyclo[3.1.0]hexane-3-carbonitrile, 2-[(2S)-2-aMino-2-(3-hydroxytricyclo[3.3.1.13,7]dec-1-yl)acetyl]-, (1S,3R,5S)-Supplier

Jiangsu Vcare PharmaTech Co., Ltd.
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Shanghai Kewel Chemical Co., Ltd.
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Tonichem Pharmaceutical Technology Co., Ltd.
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Shenzhen Polymeri Biochemical Technology Co., Ltd.
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