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LCZ696 InteMediate

Basic information Safety Supplier Related

LCZ696 InteMediate Basic information

Product Name:
LCZ696 InteMediate
Synonyms:
  • N-[(1R)-2-[1,1'-Biphenyl]-4-yl-1-(hydroxymethyl)ethyl]carbamic acid 1,1-dimethylethyl ester
  • LCZ696 InteMediate
  • (R)-tert-butyl (1-([1,1'-biphenyl]-4-yl)-3-hydroxypropan-2-yl)carbaMate
  • LCZ696(valsartan + sacubitril) impurity 29
  • (R) -tert-butyl (1-([1,1'-biphenyl] -4-yl) -3-hydroxypropane-2-yl) carbamate
  • (R)-tert-butyl (1-([1
  • 1'-biphenyl]-4-yl)-3-hydroxypropan-2-yl)carbamate
  • tert-butyl (R)-(1-([1,1'-biphenyl]-4-yl)-3-hydroxypropan-2-yl)carbamate
CAS:
1426129-50-1
MF:
C20H25NO3
MW:
327.42
EINECS:
202-804-9
Product Categories:
  • LCZ696
  • LCZ 696
  • 1426129-50-1
Mol File:
1426129-50-1.mol
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LCZ696 InteMediate Chemical Properties

Boiling point:
514.5±50.0 °C(Predicted)
Density 
1.103±0.06 g/cm3(Predicted)
storage temp. 
2-8°C
pka
11.85±0.46(Predicted)
InChI
InChI=1S/C20H25NO3/c1-20(2,3)24-19(23)21-18(14-22)13-15-9-11-17(12-10-15)16-7-5-4-6-8-16/h4-12,18,22H,13-14H2,1-3H3,(H,21,23)/t18-/m1/s1
InChIKey
TYQICOFAZDVKMK-GOSISDBHSA-N
SMILES
C(OC(C)(C)C)(=O)N[C@@H](CO)CC1=CC=C(C2=CC=CC=C2)C=C1
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LCZ696 InteMediate Usage And Synthesis

Uses

N-?[(1R)?-?2-?[1,?1''-?Biphenyl]?-?4-?yl-?1-?(hydroxymethyl)?ethyl]?-carbamic Acid 1,?1-?Dimethylethyl Ester is a useful intermediate for preparing Sacubitril (S080900)/Valsartan (V095750).

LCZ696 InteMediateSupplier

Suzhou Sino Rare Chemical Co., Ltd. Gold
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0512-62857507
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CHONGOINGJICHENG BIOPHARMACEUTICAL SCIENCE AND TECHNOLOGY CO.,LTD Gold
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023-67646862 18983213987
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Shandong Sihuan Pharmaceutical Co., Ltd. Gold
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0531-88993983 13065008173
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nora.zhang@sdsihuanpharm.com
Shandong Xuande Pharmaceutical Technology Co. LTD Gold
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18866895588
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dingjiaying@shiningpharm.com
Haoyuan Chemexpress Co., Ltd. Gold
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021-58950125
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info@chemexpress.com