Tenofovir Related Compound 4 Chemical Properties

Boiling point:

615.0±65.0 °C(Predicted)

Density 

1.50±0.1 g/cm3(Predicted)

solubility 

DMSO (Slightly), Methanol (Slightly)

pka

4.24±0.10(Predicted)

form 

Solid

color 

White to Off-White

Stability:

Hygroscopic, Unstable in Solution

InChI

InChI=1/C15H25N6O5P/c1-9(2)26-15(22)11(4)20-27(23,24)8-25-10(3)5-21-7-19-12-13(16)17-6-18-14(12)21/h6-7,9-11H,5,8H2,1-4H3,(H2,16,17,18)(H2,20,23,24)/t10-,11+/s3

InChIKey

BOVSGPQGGHVIEX-WQVXQJEGNA-N

SMILES

C(N1C=NC2=C(N=CN=C12)N)[C@@H](C)OCP(O)(=O)N[C@@H](C)C(=O)OC(C)C |&1:11,19,r|

Tenofovir Related Compound 4 Usage And Synthesis

Uses

Desphenyl Tenofovir Alafenamide belongs to a group??of tenofovir diesters compounds, which can inhibit HIV-1 virus replication.??Desphenyl Tenofovir Alafenamide can also be used to investigate the effect of oral absorption and lymphoid cell loading of GS-7340 (a prodrug of tenofovir).

Tenofovir Related Compound 4(851456-00-3)Related Product Information

• Diisopropyl Tenofovir FuMarate
• 2,4,6,8-Tetraoxa-5-phosphanonanedioic acid, 5-[[(1R)-2-[6-[[[[9-[(2R)-5-hydroxy-2,11-diMethyl-5-oxido-9-oxo-3,6,8,10-tetraoxa-5-phosphadodec-1-yl]-9H-purin-6-yl]aMino]Methyl]aMino]-9H-purin-9-yl]-1-Methylethoxy]Methyl]-, 1,9-bis(1-Methylethyl) ester, 5-ox
• P-[[(1S)-2-(6-AMino-9H-purin-9-yl)-1-Methylethoxy]Methyl]-phosphonic Acid Monoethyl Ester
• Tenofovir Alafenamide
• diisopropyl 2,2'-((((((R)-1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)phosphoryl)bis(azanediyl))(2S,2'S)-dipropionate compound with methane (1:1)
• Tenofovir Related Compound 6
• Tenofovir Related Compound 1
• Tenofovir Alafenamide Impurity 30
• TENOFOVIR-D6
• (((((1-(6-aMino-9H-purin-9-yl)propan-2-yl)oxy)Methyl)phosphoryl)bis(oxy))bis(Methylene) isopropyl Methyl dicarbonate
• isopropyl ((S)-((((R)-1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)(phenoxy)phosphoryl)-D-alaninate
• Tenofovir alafenamide hemifumarate
• Tenofovir Disopropyl Ethyl Diester
• Mono-POC Tenofovir FuMarate Salt
• ((((((R)-1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)(((isopropoxycarbonyl)oxy)methoxy)phosphoryl)oxy)methyl dimethylcarbamate
• Tenofovir disoproxil
• isopropyl ((R)-((((S)-1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)(phenoxy)phosphoryl)-L-alaninate
• GS-7340 (fuMarate)