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Macitentan impurity B

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Macitentan impurity B Basic information

Product Name:
Macitentan impurity B
Synonyms:
  • Macitentan impurity B
  • Macitentan impurity D
  • Macitentan N-Despropyl-N-Ethyl Impurity
  • Sulfamide, N-[5-(4-bromophenyl)-6-[2-[(5-bromo-2-pyrimidinyl)oxy]ethoxy]-4-pyrimidinyl]-N'-ethyl-
  • Macitentan N-Despropyl-N-Ethyl Impurity/ Macitentan N-Ethyl Analog
  • 5-(4-bromophenyl)-6-[2-(5-bromopyrimidin-2-yl)oxyethoxy]-N-(ethylsulfamoyl)pyrimidin-4-amine
  • Macitentan Impurity 04
CAS:
441796-13-0
MF:
C18H18Br2N6O4S
MW:
574.25
Mol File:
441796-13-0.mol
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Macitentan impurity B Chemical Properties

Boiling point:
686.7±65.0 °C(Predicted)
Density 
1.715±0.06 g/cm3(Predicted)
pka
6.90±0.50(Predicted)
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Macitentan impurity B Usage And Synthesis

Uses

N-Despropyl-N-ethyl Macitentan is an impurity of Macitentan (M105005); a dual orally active and potent endothelin receptor antagonist used for pulmonary arterial hypertension.

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