Basic information Safety Supplier Related

COENZYME Q1

Basic information Safety Supplier Related

COENZYME Q1 Basic information

Product Name:
COENZYME Q1
Synonyms:
  • 2,3-DIMETHOXY-5-METHYL-6-(3-METHYL-2-BUTENYL)-1,4-BENZOQUINONE
  • COENZYME Q1
  • UBIQUINONE-5
  • 2,3-dimethoxy-5-methyl-6-(3-methylbut-2-enyl)cyclohexa-2,5-diene-1,4-dione
  • Ubiquinone Q1
  • 2,3-Dimethoxy-5-methyl-6-(3-methyl-2-butenyl)-1,4-benzoquinone, Ubiquinone-1, Ubiquinone-5
  • 2,3-Dimethoxy-5-methyl-6-(3-methyl-2-butenyl)-2,5-cyclohexadiene-1,4-dione
  • 2-Isopentenyl-5,6-dimethoxy-3-methyl-p-benzoquinone
CAS:
727-81-1
MF:
C14H18O4
MW:
250.29
Mol File:
727-81-1.mol
More
Less

COENZYME Q1 Chemical Properties

Boiling point:
389.1±42.0 °C(Predicted)
Density 
1.10±0.1 g/cm3(Predicted)
storage temp. 
-20°C
solubility 
DMF: 10 mg/ml; Ethanol: 10 mg/ml
form 
Orange-red to red liquid.
color 
Orange to red
More
Less

Safety Information

Safety Statements 
23-24/25
WGK Germany 
3
More
Less

COENZYME Q1 Usage And Synthesis

Description

Cooenzyme Q10 (CoQ10) is a component of the electron transport chain and participates in aerobic cellular respiration, generating energy in the form of ATP. CoQ1 is an amphipathic CoQ10 homolog that has a tail consisting of five isoprene units. It has been used as an electron acceptor to study a range of oxidoreductases as isolated enzymes, in subcellular fractions, in intact cells in culture, and in perfused organs. Ubiquinone analogs, including CoQ1, impact mitochondrial permeability transition pore (PTP) formation, as well as PTP-dependent cell death, in an analog- and cell-specific manner.

Uses

Coenzyme Q1 has been used to measure the mitochondrial respiratory chain complex 1 activity.

Uses

Coenzyme Q1 is an electron acceptor and a component of the electron transport chain. It also play a role in the?mitochondrial permeability transition pore (PTP). Coenzyme Q1 is structurally similar to?coenzyme Q2 (C636450)?and?coenzyme Q10 (C636501).

Definition

ChEBI: Ubiquinones is any benzoquinone derived from 2,3-dimethoxy-5-methylbenzoquinone; one of a group of naturally occurring homologues. The redox-active quinoid moiety usually carries a polyprenoid side chain at position 6, the number of isoprenoid units in which is species-specific. Ubiquinones are involved in the control of mitochondrial electron transport, and are also potent anti-oxidants. It has a role as an Escherichia coli metabolite and a mouse metabolite. It is a prenylquinone and a member of 1,4-benzoquinones. It is functionally related to a 2,3-dihydroxy-5-methyl-1,4-benzoquinone.

General Description

Coenzyme Q (CoQ) is localized to the hydrophobic domain of the phospholipid bilayer of mitochondria, plasma lipoproteins, and other biological membranes. It is a ubiquinone homolog with a short isoprenoid side chain.

Biochem/physiol Actions

Coenzyme Q1 (CoQ1) is a 1 isoprenyl group (not naturally occurring) member of a family of ubiquinones that share a quinine chemical group but differ in the number of isoprenyl chemical subunits in their tail. The CoQ compounds are lipid soluble components of cell membranes where they perform multiple functions such as electron and proton transport. The most well studied CoQ compound is CoQ10. CoQ1 is frequently used in comparison studies on the effect of isoprenyl chain length on CoQ functions or distribution and to identify quinone reductases.

COENZYME Q1Supplier

Sigma-Aldrich
Tel
021-61415566 800-8193336
Email
orderCN@merckgroup.com
Shanghai EFE Biological Technology Co., Ltd.
Tel
021-65675885 18964387627
Email
info@efebio.com
Shenzhen Regent Biochemical Technology Co., Ltd.
Tel
0755-0755-85201366 18938635012
Email
sales@regentsciences.com
Rhawn Reagent
Tel
400-400-1332688 18019345275
Email
amy@rhawn.cn
Beijing OKA biological technology co., LTD
Tel
010-010-010-62971590 18548936886
Email
jack@oka-vip.com