3,3',4,4'-Biphenyltetramine tetrahydrochloride Chemical Properties

Melting point:

300°C

storage temp. 

2-8°C

solubility 

DMSO (Slightly), Methanol (Slightly), Water (Slightly)

form 

tablets

color 

Crystals

PH

pH(25℃) : 7.4～7.8

Water Solubility 

Soluble

Sensitive 

Moisture Sensitive/Air Sensitive

BRN 

1212988

Stability:

Hygroscopic

CAS DataBase Reference

7411-49-6(CAS DataBase Reference)

EPA Substance Registry System

[1,1'-Biphenyl]-3,3',4,4'-tetramine, tetrahydrochloride (7411-49-6)

Safety Information

Hazard Codes 

F,T,Xn,N

Risk Statements 

23/24/25-36/38-39/23/24/25-40-20/21/22-68-45-51/53-42/43-60-61

Safety Statements 

7-16-24-33-36/37-45-24/25-22-36/37/39-53-61

RIDADR 

UN 3316 9/PG 2

WGK Germany 

3

RTECS 

DV8753000

F 

3-8-10

HS Code 

29215900

Hazardous Substances Data

7411-49-6(Hazardous Substances Data)

Toxicity

LD50 ipr-mus: 330 mg/kg NCIBR* NIH-NCI-E-68-1311,10,73

MSDS

• Language:English Provider:3,3',4,4'-Biphenyltetramine tetrahydrochloride
• Language:English Provider:SigmaAldrich

3,3',4,4'-Biphenyltetramine tetrahydrochloride Usage And Synthesis

Chemical Properties

Grey Solid

Uses

A substrate for peroxidase, and a reagent for the spectrophotometric determination of selenium

Uses

3,3′-Diaminobenzidine (DAB) Enhanced Liquid Substrate System tetrahydrochloride has been used:

• in the detection of hydrogen peroxide in rice leaves
• as a substrate for rabbit peroxidase in immunohistochemistry of mice brain sections
• in immunocytochemistry of muscle-derived stem cells (MDSCs)

Uses

3,3′-Diaminobenzidine tetrahydrochloride has been used for immunohistochemistry.

General Description

3,3′-Diaminobenzidine (DAB) is a chromogenic substrate for peroxidase enzyme. It is converted to an insoluble precipitate after oxidation by peroxidase.

Biochem/physiol Actions

3,3′-Diaminobenzidine (DAB) is a chromogenic substrate for peroxidase enzyme. It is converted to an insoluble precipitate after oxidation by peroxidase. This feature is exploited for visualization in histochemical (HC) and immunohistochemical (IHC) staining.

Safety Profile

Suspected carcinogen withexperimental neoplastigenic and tumorigenic data. Poisonby intraperitoneal route. When heated to decomposition itemits very toxic fumes of HCl and NOx.

Purification Methods

Dissolve the salt in water and precipitate it by adding conc HCl, then drying it over solid NaOH. [Beilstein 13 IV 530.]

3,3',4,4'-Biphenyltetramine tetrahydrochloride(7411-49-6)Related Product Information

• Aminoacetonitrile hydrochloride
• 3,3'-Diaminobenzidine
• Benzidine dihydrochloride
• Benzidine
• Aniline hydrochloride
• AMINOGUANIDINE HYDROCHLORIDE
• Pigment Yellow 12
• D-Glucosamine hydrochloride
• 3,3',5,5'-Tetramethylbenzidine dihydrochloride
• FMOC-DAB-OH HCL
• 3,3',4,4'-Biphenyltetramine tetrahydrochloride dihydrate,3,3μ,4,4μ-Biphenyltetramine tetrahydrochloride, 3,3μ,4,4μ-Tetraaminobiphenyl tetrahydrochloride
• 3,3'-Diaminobenzidine tetrahydrochloride hydrate
• H-DAB-OH HCL
• DL-DAB 2HCL
• D-DAB 2HCL,D-DAB·2HCL,D-2,4-DIAMINOBUTYRIC ACID DIHYDROCHLORIDE
• M-XENYLAMINE HYDROCHLORIDE
• 3,4-DIAMINOBIPHENYL DIHYDROCHLORIDE
• FMOC-D-DAB-OH HCL