2-Phenylbutyryl chloride Chemical Properties

Melting point:

178-180 °C

Boiling point:

122-125 °C/20 mmHg (lit.)

Density 

1.093 g/mL at 25 °C (lit.)

refractive index 

n20/D 1.516(lit.)

Flash point:

209 °F

storage temp. 

Inert atmosphere,Room Temperature

solubility 

Chloroform, Hexanes

form 

Oil

color 

Colourless to Light Yellow

Specific Gravity

1.090

Sensitive 

Moisture Sensitive

BRN 

2045209

CAS DataBase Reference

36854-57-6(CAS DataBase Reference)

NIST Chemistry Reference

2-Phenylbutyryl chloride(36854-57-6)

Safety Information

Hazard Codes 

C

Risk Statements 

34

Safety Statements 

22-26-27-36/37/39-45

RIDADR 

UN 3265 8/PG 2

WGK Germany 

3

RTECS 

ET5957500

HazardClass 

8

PackingGroup 

II

HS Code 

29130000

MSDS

• Language:English Provider:2-Phenylbutyryl chloride
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2-Phenylbutyryl chloride Usage And Synthesis

Chemical Properties

Clear pale yellow to yellow liquid

Uses

α-Ethyl-benzeneacetyl Chloride is used in the synthesis of mild and neutral system for selective reduction of organic functional groups. Also used in the preparation of phenothiazine derivatives for the reversible inhibition of human butyrylcholinesterase.

Uses

(R)-(-)-2-phenylbutyryl chloride may be employed as chiral reagent for the determination of dopamine and dopamine-derived salsolinol and norsalsolinol in human brain by GC-MS method. Chiral (S)-(+)-2-phenylbutyryl chloride may be used as derivatization reagent for the hydroxyl groups during the GC-MS assay for the enantiomers of 1,2-propanediol, 1,3-butanediol, 1,3-pentanediol and their corresponding hydroxyacids in biological fluids.

General Description

The kinetic resolution of racemic 2-phenylbutyryl chloride by sterically hindered chiral secondary alcohols has been evaluated. 2-Phenylbutyryl chloride reacts with 4-methoxybenzoyl chloride catalyzed by PdBr(Ph)(PPh₃)₂ to yield 1-(4-methoxyphenyl)-2-phenyl-2-buten-1-one.

2-Phenylbutyryl chloride(36854-57-6)Related Product Information

• Polyvinyl chloride
• 2,2-Dimethylbutyryl chloride
• Isobutyryl chloride
• Oxalyl chloride
• Mepiquat chloride
• Chloroacetyl chloride
• Sulfuryl chloride
• Benzyl chloride
• Tosyl chloride
• Ammonium chloride
• 3,3-Dimethylbutyryl chloride
• Benzoyl chloride
• Sodium chloride
• Calcium chloride
• Butyryl chloride
• Choline chloride
• Phenylacetyl chloride
• 2-Phenylbutyric acid