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Vindoline

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Vindoline Basic information

Product Name:
Vindoline
Synonyms:
  • aspidospermidine-3-carboxylicacid,4-(acetyloxy)-6,7-didehydro-3-hydroxy-16-me
  • thoxy-1-methyl-,methylester,(2-beta,3-beta,4-beta,5-alpha,12-beta,19-alpha)
  • vindolin
  • (2beta,3beta,4beta,5alpha,12beta,19alpha)-4-(acetyloxy)-6,7-didehydro-3-hydroxy-16-methoxy-1-methyl-aspidospermidine-3-carboxylic acid methyl ester
  • VINDOLINE
  • Aspidospermidine-3-carboxylic acid, 4-(acetyloxy)-6,7-didehydro-3-hydroxy-16-methoxy-1-methyl-, methyl ester, (2beta,3beta,4beta,5alpha,12beta,19alpha)-
  • (2,3,4,5a,12,19a)-4-(Acetyloxy)-6,7-didehydro-3-hydroxy-16-methoxy-1-methyl-aspidospermidine-3-carboxylic Acid Methyl Ester
  • NSC 91994
CAS:
2182-14-1
MF:
C25H32N2O6
MW:
456.53
EINECS:
218-558-0
Product Categories:
  • Alkaloids
  • Inhibitors
  • chemical reagent
  • pharmaceutical intermediate
  • phytochemical
  • reference standards from Chinese medicinal herbs (TCM).
  • Miscellaneous Biochemicals
  • Chiral Reagents
  • Intermediates & Fine Chemicals
  • Pharmaceuticals
  • standardized herbal extract
Mol File:
2182-14-1.mol
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Vindoline Chemical Properties

Melting point:
163-1650C
alpha 
D20 -18° (chloroform); D27 +42° (chloroform)
Boiling point:
569.8±50.0 °C(Predicted)
Density 
1.33±0.1 g/cm3(Predicted)
storage temp. 
-20°C Freezer
solubility 
Chloroform (Slightly), Ethanol (Slightly), Methanol (Slightly)
pka
5.5 in 66% DMF (Moza, Trojánek)
form 
White to off-white crystalline powder.
color 
White to Off-White
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Safety Information

Hazard Codes 
Xn
Risk Statements 
68
Safety Statements 
36/37-24/25
HS Code 
29339900

MSDS

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Vindoline Usage And Synthesis

Chemical Properties

Off-White Solid

Uses

Vindoline is a novel antitumor agent.

Definition

ChEBI: Vindoline is a vinca alkaloid, an alkaloid ester, an organic heteropentacyclic compound, a methyl ester, an acetate ester, a tertiary amino compound and a tertiary alcohol. It is a conjugate base of a vindolinium(1+).

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