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Linagliptin Impurity H

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Linagliptin Impurity H Basic information

Product Name:
Linagliptin Impurity H
Synonyms:
  • Linagliptin Impurity H
  • 1-((4-methylquinazolin-2-yl)methyl)piperidin-3-amine
  • Linagliptin impurity 12/7-(2-Butyn-1-yl)-8-(dimethylamino)-3,7-dihydro-3-methyl-1-[(4-methyl-2-quinazolinyl)methyl]-1H-purine-2,6-dione
  • Linagliptin Imp.K
  • 1H-Purine-2,6-dione, 7-(2-butyn-1-yl)-8-(dimethylamino)-3,7-dihydro-3-methyl-1-[(4-methyl-2-quinazolinyl)methyl]-
  • Linagliptin H
  • 7-(but-2-yn-1-yl)-8-(dimethylamino)-3-methyl-1-((4-methylquinazolin-2-yl)methyl)-3,7-dihydro-1H-purine-2,6-dione
  • 7-(But-2-yn-1-yl)-8-(dimethylamino)-3-methyl-1-((4-methylquinazolin-2-yl)methyl)-1H-purine-2,6(3H,7H)-dione (Linagliptin Impurity)
CAS:
1646355-34-1
MF:
C22H23N7O2
MW:
417.46
Mol File:
1646355-34-1.mol
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Linagliptin Impurity H Chemical Properties

Boiling point:
583.0±60.0 °C(Predicted)
Density 
1.30±0.1 g/cm3(Predicted)
pka
2.47±0.50(Predicted)
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Linagliptin Impurity H Usage And Synthesis

Uses

7-(But-2-yn-1-yl)-8-(dimethylamino)-3-methyl-1-((4-methylquinazolin-2-yl)methyl)-1H-purine-2,6(3H,7H)-dione is an impurity of Linagliptin (L465900), a novel potent and selective dipeptidyl peptidase-4 (DPP-4) inhibitor with potential use in the treatment of type 2 diabetes.

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