ChemicalBook > Product Catalog > Pharmaceutical intermediates > Heterocyclic compound > Quinoline compounds > 5,7-Dichloro-8-hydroxyquinoline
5,7-Dichloro-8-hydroxyquinoline
5,7-Dichloro-8-hydroxyquinoline Basic information
- Product Name:
- 5,7-Dichloro-8-hydroxyquinoline
- Synonyms:
-
- 5,7-Dichlor-8-hydroxychinolin
- 5,7-Dichloro-8-hydroquinoline
- 5,7-Dichloro-8-hydroxyquinolin
- 5,7-Dichloro-8-oxychinolin
- 5,7-Dichloro-8-oxyquinoline
- 5,7-dichloro-8-quinolino
- 5,7-Dichlorooxine
- 5,7-Dichloroxine
- CAS:
- 773-76-2
- MF:
- C9H5Cl2NO
- MW:
- 214.05
- EINECS:
- 212-258-3
- Product Categories:
-
- CINAZYN
- Building Blocks
- C8 to C10
- Chemical Synthesis
- Halogenated Heterocycles
- Heterocyclic Building Blocks
- Quinolines, Quinazolines and derivatives
- Haloquinolines
- Hydroxyquinolines
- Quinolines
- Mol File:
- 773-76-2.mol
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5,7-Dichloro-8-hydroxyquinoline Chemical Properties
- Melting point:
- 178-180 °C (lit.)
- Boiling point:
- 305.47°C (rough estimate)
- Density
- 1.3320 (rough estimate)
- refractive index
- 1.5500 (estimate)
- storage temp.
- Sealed in dry,Room Temperature
- solubility
- Chloroform (Slightly), DMSO (Slightly, Heated, Sonicated), Methanol (Slightly, Heated, Sonicated)
- pka
- 2.30±0.30(Predicted)
- form
- Fluffy Powder
- color
- Light beige
- Merck
- 14,2175
- BRN
- 153606
- Stability:
- Light Sensitive
- CAS DataBase Reference
- 773-76-2(CAS DataBase Reference)
- NIST Chemistry Reference
- 8-Quinolinol, 5,7-dichloro-(773-76-2)
- EPA Substance Registry System
- 8-Quinolinol, 5,7-dichloro- (773-76-2)
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Safety Information
- Hazard Codes
- Xn,Xi
- Risk Statements
- 22-37/38-41-36/37/38
- Safety Statements
- 26-36-37/39-25-22
- WGK Germany
- 3
- RTECS
- VC5350000
- TSCA
- Yes
- HS Code
- 29334900
MSDS
- Language:English Provider:5,7-Dichloro-8-quinolinol
- Language:English Provider:SigmaAldrich
- Language:English Provider:ACROS
- Language:English Provider:ALFA
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5,7-Dichloro-8-hydroxyquinoline Usage And Synthesis
Chemical Properties
light beige fluffy powder
Uses
H1 antihistamine
Uses
Analytical reagent.
Uses
Chloroxine, is an impurity of Cioquinol, which is an antifungal and antiprotozoal drug.
Indications
Chloroxine (Capitrol) shampoo contains a synthetic antibacterial compound similar to the hydroxyquinoline compounds used in dermatology for many years.
Definition
ChEBI: Quinolin-8-ol in which the hydrogens at positions 5 and 7 have been substituted by chlorine. An synthetic antibacterial prepared by chlorination of quinolin-8-ol, it is used for the treatment of dandruff and seborrhoeic dermatitis of the scalp.
brand name
Capitrol (Westwood- Squibb).
Purification Methods
Crystallise the dichloro-oxine from acetone/EtOH. [Beilstein 21 H 95.]
5,7-Dichloro-8-hydroxyquinoline Preparation Products And Raw materials
Raw materials
5,7-Dichloro-8-hydroxyquinolineSupplier
J & K SCIENTIFIC LTD.
- Tel
- 010-82848833 400-666-7788
- jkinfo@jkchemical.com
Meryer (Shanghai) Chemical Technology Co., Ltd.
- Tel
- 4006608290; 18621169109
- market03@meryer.com
Alfa Aesar
- Tel
- 400-6106006
- saleschina@alfa-asia.com
TAIYUAN RHF CO.,LTD.
- Tel
- +86 351 7031519
- sales@RHFChem.com
TCI (Shanghai) Development Co., Ltd.
- Tel
- 021-67121386
- Sales-CN@TCIchemicals.com
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5,7-Dichloro-8-hydroxyquinoline(773-76-2)Related Product Information
- N,N-Dimethylacetamide
- Sodium dichloroisocyanurate
- Dichlorodimethylsilane
- Quinclorac
- 8-Hydroxyquinoline
- 5-Chloro-8-hydroxyquinoline
- Quinhydrone
- Thionyl chloride
- Dichloroethane
- 6,8-DICHLORO-4-HYDROXYQUINOLINE
- 2-METHYL-5,7-DICHLORO-8-HYDROXYQUINOLINE
- 5,8-DICHLORO-4-HYDROXYQUINOLINE
- 5,7-DICHLORO-4-HYDROXYQUINOLINE-3-CARBOXYLIC ACID
- Halquinol
- 5,7-DICHLORO-8-QUINOLYL 2-CHLORONICOTINATE
- CHEMBRDG-BB 5175177
- 6,8-DICHLORO-4-HYDROXYQUINOLINE-3-CARBOXYLIC ACID ETHYL ESTER,ETHYL 6,8-DICHLORO-4-HYDROXYQUINOLINE-3-CARBOXYLATE
- 6,8-DICHLORO-4-HYDROXYQUINOLINE-3-CARBOXYLIC ACID