N-Boc-PEG6-alcohol
N-Boc-PEG6-alcohol Basic information
- Product Name:
- N-Boc-PEG6-alcohol
- Synonyms:
-
- N-Boc-PEG6-alcohol
- Boc-NH-PEG6-OH
- t-boc-N-amido-PEG6-alcohol
- N-Boc-PEG6-alcohol,BocNH-PEG6-OH
- 2-[2-(2-{2-[2-(2-hydroxyethoxy)ethoxy]ethoxy}ethoxy)ethoxy]ethyl tert-butylcarbamate
- NHBoc-PEG6-OH
- 17-(Boc-amino)-3,6,9,12,15-pentaoxa-1-heptadecanol
- tert-Butyl(17-hydroxy-3,6,9,12,15-pentaoxaheptadecyl)carbamate
- CAS:
- 331242-61-6
- MF:
- C17H35NO8
- MW:
- 381.46
- Product Categories:
-
- peg
- Mol File:
- 331242-61-6.mol
N-Boc-PEG6-alcohol Chemical Properties
- Boiling point:
- 487.1±45.0 °C(Predicted)
- Density
- 1.087±0.06 g/cm3(Predicted)
- solubility
- Soluble in DMSO, DCM, DMF
- pka
- 12.23±0.46(Predicted)
N-Boc-PEG6-alcohol Usage And Synthesis
Description
N-Boc-PEG6-alcohol is a PEG linker containing a Boc protected amine group and a terminal hydroxyl group. The Boc protecting group can be removed under acidic conditions. The hydroxyl group can react to further derivatize the compound. The hydrophilic PEG linker increases the water solubility of the compound.
Uses
N-Boc-PEG6-alcohol is a PROTAC bridge that belongs to the PEG class and the Alkyl/ether class. N-Boc-PEG6-alcohol can be used to synthesize a series of PROTAC molecules from Chemicalbook. N-Boc-PEG6-alcohol is a cleavable ADC bridge for the synthesis of antibody drug conjugates (ADCs).
in vitro
PROTACscontaintwodifferentligandsconnectedbyalinker;oneisaandforanE3ubiquitinligaseandtheotherisforthetargetprotein.PROTACsexploittheintracelChemicalbooklularubiquitin-proteasomesystemtoselectivelydegradetargetproteins.ADCsarecomprisedofanantibodytowhichisattachedanADCcytotoxinthroughanADClinker.
N-Boc-PEG6-alcoholSupplier
- Tel
- 400-0255188 4000255188
- sales@pharmablock.com
- Tel
- 0512-58900862 400-0707518
- sales@alabiochem.com
- Tel
- 0757-86329057 18934348241
- sales4.gd@hwrkchemical.com
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- 021-021-58432009 400-005-6266
- sales8178@energy-chemical.com
- Tel
- 021-50795510 4000665055
- sales@accelachem.com
N-Boc-PEG6-alcohol(331242-61-6)Related Product Information
- t-Boc-N-amido-PEG8-acid
- N-BOC-AMINOEHTOXY-ETHOXY-ETHOXY-ETHANOL
- O-(2-AMinoethyl)-O'-[2-(Boc-aMino)ethyl]tetraethylene Glycol
- 5,8,11-Trioxa-2-azatridecanoic,13-amino,1,1-dimethylethyl ester
- O-[2-(Boc-amino)ethyl]-Oμ-(2-carboxyethyl)polyethylene glycol 3,000
- Carbamic acid, [2-(2-aminoethoxy)ethyl]-, 1,1-dimethylethyl ester (9CI)
- O-(2-AMINOETHYL)-O-(2-(BOC-AMINO)ETHYL)OCTAETHYLENE GLYCOL
- BOC-21-AMINO-4,7,10,13,16,19-HEXAOXAHENEICOSANOIC ACID
- BOC-15-AMINO-4,7,10,13-TETRAOXAPENTADECANOIC ACID
- Z-8-aMino-3,6-dioxaoctanoic acid
- t-Boc-N-amido-PEG5-acid
- Boc-9-AMino-4,7-Dioxanonanoic acid
- 5,8,11,14-Tetraoxa-2-azahexadecanoic acid,16-amino-,1,1-dimethyl ester
- O-(2-AMINOETHYL)-O'-(2-(BOC-AMINO)ETHYL)
- t-Boc-N-amido-PEG2-acid
- 2,2-DIMETHYL-4-OXO-3,8,11,14-TETRAOXA-5-AZAHEXADECAN-16-OIC ACID
- t-Boc-N-amido-PEG1-acid
- 3,8,11-Trioxa-5-azatridecan-13-oic acid, 2,2-diMethyl-4-oxo-