(R)-(-)-3-Hydroxytetrahydrofuran Chemical Properties

alpha 

-18.5 º (c=2 MeOH)

Boiling point:

181 °C (lit.)

Density 

1.097 g/mL at 25 °C (lit.)

refractive index 

n20/D 1.45(lit.)

Flash point:

180 °F

storage temp. 

Keep in dark place,Sealed in dry,Room Temperature

solubility 

Chloroform, Methanol (Slightly)

pka

14.49±0.20(Predicted)

form 

Liquid

Specific Gravity

1.097

color 

Clear colorless

optical activity

[α]20/D 18°, c = 2.4 in methanol

InChI

InChI=1S/C4H8O2/c5-4-1-2-6-3-4/h4-5H,1-3H2/t4-/m1/s1

InChIKey

XDPCNPCKDGQBAN-SCSAIBSYSA-N

SMILES

O1CC[C@@H](O)C1

CAS DataBase Reference

86087-24-3(CAS DataBase Reference)

Safety Information

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

26-36

RIDADR 

NA 1993 / PGIII

WGK Germany 

3

HS Code 

29321900

MSDS

• Language:English Provider:SigmaAldrich

(R)-(-)-3-Hydroxytetrahydrofuran Usage And Synthesis

Chemical Properties

Colorless to light yellow liqui

Uses

(R)-(-)-3-Hydroxytetrahydrofuran is used as a chemical reactant in the synthesis of pharmaceutical agents. Empagliflozin is synthesized using this reactant

Uses

(R)-(-)-3-Hydroxytetrahydrofuran may be used as building block in the synthesis of potent HIV protease inhibitors.

(R)-(-)-3-Hydroxytetrahydrofuran(86087-24-3)Related Product Information

• 2-Methyltetrahydrofuran
• Tetrahydrofuran
• 2,3,4,6-TETRA-O-PIVALOYL-ALPHA-D-GLUCOPYRANOSYL BROMIDE
• Acetoxy Empagliflozin
• (2-Chloro-5-iodophenyl)(4-fluorophenyl)methanone
• (R)-3-(4-(5-broMo-2-chlorobenzyl)phenoxy)tetrahydrofuran
• (3R,4S,5S,6R)-2-[4-chloro-3-[[4-[(3S)-oxolan-3-yl]oxyphenyl]methyl]phenyl]-6-(hydroxymethyl)-2-methoxyoxane-3,4,5-triol
• EMpagliflozin iMpurity 10
• Butanoic acid, 4-chloro-3-hydroxy-, (3S)-
• Methanone, (5-chloro-2-iodophenyl)(2-fluorophenyl)-
• (5-bromo-2-chlorophenyl)(4-fluorophenyl)methanone
• 1-chloro-4-(β-D-glucopyranos-1-yl)-2-[4-((S)-tetrahydrofuran-3-yloxy)benzyl]benzene
• Empagliflozin Impurity 32
• 4-(pyridine-2-yl) pyrimidin-2-amine
• (2-Chloro-5-iodophenyl)[4-[[(3S)-tetrahydro-3-furanyl]oxy]phenyl]methanone
• (S)-(5-broMo-2-chlorophenyl)(4-(tetrahydrofuran-3-yloxy)phenyl)Methanone
• EMpagliflozin iMpurity 13
• Empagliflozin Impurity