ChemicalBook > Product Catalog > API > Antipyretic analgesics > Nonsteroidal Anti-Inflammatory Drugs (NSAIDS) > Loxoprofen
Loxoprofen
Loxoprofen Basic information
- Product Name:
- Loxoprofen
- Synonyms:
-
- IOXOPROFEN
- 2-[4-[(2-Oxocyclopentan-1-yl)methyl]phenyl]propionic acid
- KOLOXO
- LOXOPROFEN
- 2-[4-(2-OXO-CYCLOPENTYLMETHYL)-PHENYL]-PROPIONIC ACID
- A-METHYL-4-[(2-OXOCYCLOPENTYL)METHYL]BENZENEACETIC ACID
- α-methyl-4-[(2-oxocyclopentyl)methyl]benzeneacetic acid
- 2-{4-[(2-oxocyclopentyl)methyl]phenyl}propanoic acid
- CAS:
- 68767-14-6
- MF:
- C15H18O3
- MW:
- 246.31
- EINECS:
- 1806241-263-5
- Product Categories:
-
- LOXONIN
- Active Pharmaceutical Ingredients
- Mol File:
- 68767-14-6.mol
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Loxoprofen Chemical Properties
- Melting point:
- 108.5-111°
- Boiling point:
- bp0.3 190-195°
- Density
- 1.182±0.06 g/cm3(Predicted)
- storage temp.
- Sealed in dry,Room Temperature
- solubility
- Chloroform (Slightly), Methanol (Slightly)
- form
- solid
- pka
- 4.39±0.10(Predicted)
- color
- White to Off-White
- Merck
- 14,5589
- InChI
- InChI=1S/C15H18O3/c1-10(15(17)18)12-7-5-11(6-8-12)9-13-3-2-4-14(13)16/h5-8,10,13H,2-4,9H2,1H3,(H,17,18)
- InChIKey
- YMBXTVYHTMGZDW-UHFFFAOYSA-N
- SMILES
- C(C1CCCC1=O)C1C=CC(C(C)C(=O)O)=CC=1
- CAS DataBase Reference
- 68767-14-6(CAS DataBase Reference)
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Safety Information
- Safety Statements
- 22-24/25
- WGK Germany
- 3
- HS Code
- 2918.99.3000
MSDS
- Language:English Provider:2-{4-[(2-Oxocyclopentyl)methyl]phenyl}propanoic acid
- Language:English Provider:SigmaAldrich
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Loxoprofen Usage And Synthesis
Uses
antiinflammatory, analgesic
Uses
Loxoprofen is a non-selective nonsteroidal anti-inflammatory drug (NSAID) that has been effective in reducing atherosclerosis in mice by reducing inflammation. Loxoprofen becomes active after metabolism in the body and inhibits the activation of cyclooxygenase.
Definition
ChEBI: A monocarboxylic acid that is propionic acid in which one of the hydrogens at position 2 is substituted by a 4-[(2-oxocyclopentyl)methyl]phenyl group. A prodrug that is rapidly converted to its active trans-alcohol metabolite following ora administration.
Loxoprofen Preparation Products And Raw materials
Raw materials
LoxoprofenSupplier
Wuhan Boye Technology Development Co., Ltd. Gold
- Tel
- 027-81625225 15377010747
- hui@boyechemicals.com
J & K SCIENTIFIC LTD.
- Tel
- 010-82848833 400-666-7788
- jkinfo@jkchemical.com
future industrial shanghai co., ltd
- Tel
- 400-0066400 13621662912
- sales@jonln.com
Energy Chemical
- Tel
- 021-021-58432009 400-005-6266
- sales8178@energy-chemical.com
Adamas Reagent, Ltd.
- Tel
- 400-6009262 16621234537
- chenyj@titansci.com
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Loxoprofen(68767-14-6)Related Product Information
- Chlorodimethylphenylsilane
- Kresoxim-methyl
- Methyl salicylate
- Methylcyclopentane
- Methanol
- Methylparaben
- Tribenuron methyl
- Tri(o-tolyl)phosphine
- Propionic acid
- Methyl acrylate
- PHENYL VALERATE
- 2,2-Bis(hydroxymethyl)propionic acid
- Basic Violet 1
- Cyclopentane
- Silicone oil (high temperature)
- Loxoprofen Related Compound 5
- Loxoprofen Related Compound 13
- 2-[(4-Acetylphenyl)methyl]cyclopentan-1-one