Basic information Safety Supplier Related

5-amino-2-hydroxy-4-sulfobiphenyl-3-carboxylicacid

Basic information Safety Supplier Related

5-amino-2-hydroxy-4-sulfobiphenyl-3-carboxylicacid Basic information

Product Name:
5-amino-2-hydroxy-4-sulfobiphenyl-3-carboxylicacid
Synonyms:
  • 5-Amino-3-(4-sulfonylphenyl)salicyclic Acid
  • 3-(4-Sulfophenyl)-5-aminosalicylic Acid RS*
  • Mesalamine EP Impurity P
  • 5-amino-2-hydroxy-4'-sulfo-[1,1'-biphenyl]-3-carboxylic acid
  • Mesalazine EP Impurity P
  • 5-Amino-2-hydroxy-4
  • Mesalazine Impurity 16(Mesalazine EP Impurity P)
  • Mesalazine (Mesalamine) EP Impurity P
CAS:
887256-40-8
MF:
C13H11NO6S
MW:
309.29
Mol File:
887256-40-8.mol
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5-amino-2-hydroxy-4-sulfobiphenyl-3-carboxylicacid Chemical Properties

Melting point:
>272°C (dec.)
storage temp. 
Hygroscopic, -20°C Freezer, Under inert atmosphere
solubility 
DMSO (Slightly)
form 
Solid
color 
White to Light Brown
Stability:
Hygroscopic
InChI
InChI=1S/C13H11NO6S/c14-8-5-10(12(15)11(6-8)13(16)17)7-1-3-9(4-2-7)21(18,19)20/h1-6,15H,14H2,(H,16,17)(H,18,19,20)
InChIKey
JFHCLENXDPFHHY-UHFFFAOYSA-N
SMILES
C1(C2=CC=C(S(O)(=O)=O)C=C2)=CC(N)=CC(C(O)=O)=C1O
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5-amino-2-hydroxy-4-sulfobiphenyl-3-carboxylicacid Usage And Synthesis

Uses

5-Amino-2-hydroxy-4''-sulfo[1,1''-biphenyl]-3-carboxylic Acid is the free form of 5-Amino-2-hydroxy-4''-sulfo[1,1''-biphenyl]-3-carboxylic Acid Hydrochloride (A629343), which is the hydrochloride salt of 5-Amino-3-(4-sulfonylphenyl)salicyclic Acid Sodium Salt (A629340), an impurity of mesalamine (M258100) that is the active metabolite of Sulfasalazine (S699084). Anti-inflammatory (gastrointestinal).

IC 50

PPAR; PAK1; NF-κB

5-amino-2-hydroxy-4-sulfobiphenyl-3-carboxylicacidSupplier

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