3-COUMARANONE Chemical Properties

Melting point:

101-103 °C

Boiling point:

207.23°C (rough estimate)

Density 

1.1603 (rough estimate)

refractive index 

1.4800 (estimate)

storage temp. 

Keep in dark place,Sealed in dry,Store in freezer, under -20°C

solubility 

Chloroform (Slightly), DMSO (Slightly)

form 

Solid

color 

Yellow to Dark Yellow

Water Solubility 

Slightly miscible with water.

Sensitive 

Light Sensitive

BRN 

115296

CAS DataBase Reference

7169-34-8(CAS DataBase Reference)

NIST Chemistry Reference

3(2H)-benzofuranone(7169-34-8)

Safety Information

Hazard Codes 

Xi,Xn

Risk Statements 

36/37/38-20/21/22

Safety Statements 

22-24/25-36/37/39-26-36

WGK Germany 

3

F 

4.5-9

Hazard Note 

Irritant

HS Code 

29329990

MSDS

• Language:English Provider:SigmaAldrich
• Language:English Provider:ALFA

3-COUMARANONE Usage And Synthesis

Chemical Properties

white to light yellow crystal powde

Uses

3-Coumaranone is used in the aurones, [2-benzylidenebenzofuran-3(2H)-ones] by reacting with appropriate aldehyde. It is involved in the condensation reaction with aldehydes in the presence of morpholine acetate to prepare substituted 2-(arylidene)benzofuran-3(ZH)-ones. In Horner-Wadsworth-Emmons reaction, it reacts with diethyl? cyanomethyl?phosphonate to give 3-(cyanomethyl)benzofurans, which is an intermediate in the synthesis of antihyperglycemic agents.

General Description

Benzofuran-3(2H)-one undergoes condensation with aldehydes in the presence of morpholine acetate to yield substituted 2-(arylidene)benzofuran-3(ZH)-ones. It undergoes acid- or base-catalyzed condensation with an appropriate aldehyde to yield aurones [2-benzylidenebenzofuran-3(2H)-ones].

3-COUMARANONE(7169-34-8)Related Product Information

• 3-COUMARANONE
• 6-HYDROXY-3-COUMARANONE
• 5-CHLORO-BENZOFURAN-3-ONE
• (+)-Griseofulvin
• AUREUSIDIN(RG)
• 7-METHOXY-3(2H)-BENZOFURANONE
• MARITIMEIN
• 3-Ketocarbofuranphenol
• Rifamycin Sodium
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• 3-BROMO-2-COUMARANONE
• 2-Coumaranone,99%,2-COUMARANONE
• 5-HYDROXY-2-COUMARANONE
• 2H-BEZOFURAN-3-ONE 3-COUMARANONE
• 2-ETHOXYCARBONYL-3-COUMARANONE,2-Carboethoxy-3-coumaranone
• 2,3-Dihydrobenzofuran
• SULFURETIN