ChemicalBook > Product Catalog > Analytical Chemistry > Standard > Pharmaceutical Impurity Reference Standards > 4-[6-[(8-cyclopentyl-6-ethenyl-7,8-dihydro-5-methyl-7-oxopyrido[2,3-d]pyrimidin-2-yl)amino]-3-pyridinyl]-1-piperazinecarboxylic acid tert-butyl ester
4-[6-[(8-cyclopentyl-6-ethenyl-7,8-dihydro-5-methyl-7-oxopyrido[2,3-d]pyrimidin-2-yl)amino]-3-pyridinyl]-1-piperazinecarboxylic acid tert-butyl ester
4-[6-[(8-cyclopentyl-6-ethenyl-7,8-dihydro-5-methyl-7-oxopyrido[2,3-d]pyrimidin-2-yl)amino]-3-pyridinyl]-1-piperazinecarboxylic acid tert-butyl ester Basic information
- Product Name:
- 4-[6-[(8-cyclopentyl-6-ethenyl-7,8-dihydro-5-methyl-7-oxopyrido[2,3-d]pyrimidin-2-yl)amino]-3-pyridinyl]-1-piperazinecarboxylic acid tert-butyl ester
- Synonyms:
-
- Palbociclib Impurity 50
- Palbociclib-020
- 1-Piperazinecarboxylic acid, 4-[6-[(8-cyclopentyl-6-ethenyl-7,8-dihydro-5-methyl-7-oxopyrido[2,3-d]pyrimidin-2-yl)amino]-3-pyridinyl]-, 1,1-dimethylethyl ester
- 4-?[6-?[(8-?Cyclopentyl-?6-?ethenyl-?7,?8-?dihydro-?5-?methyl-?7-?oxopyrido[2,?3-?d]?pyrimidin-?2-?yl)?amino]?-?3-?pyridinyl]?-1-?Piperazinecarboxylic Acid 1,?1-?Dimethylethyl Ester
- 4-[6-[(8-cyclopentyl-6-ethenyl-7,8-dihydro-5-methyl-7-oxopyrido[2,3-d]pyrimidin-2-yl)amino]-3-pyridinyl]-1-piperazinecarboxylic acid tert-butyl ester
- CAS:
- 1941177-45-2
- MF:
- C29H37N7O3
- MW:
- 531.65
- Mol File:
- 1941177-45-2.mol
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4-[6-[(8-cyclopentyl-6-ethenyl-7,8-dihydro-5-methyl-7-oxopyrido[2,3-d]pyrimidin-2-yl)amino]-3-pyridinyl]-1-piperazinecarboxylic acid tert-butyl ester Chemical Properties
- Melting point:
- >220°C (dec.)
- storage temp.
- Amber Vial, -20°C Freezer, Under inert atmosphere
- solubility
- Dichloromethane (Slightly, Heated), DMSO (Slightly, Heated, Sonicated)
- form
- Solid
- color
- Light Yellow to Dark Beige
- Stability:
- Light Sensitive
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4-[6-[(8-cyclopentyl-6-ethenyl-7,8-dihydro-5-methyl-7-oxopyrido[2,3-d]pyrimidin-2-yl)amino]-3-pyridinyl]-1-piperazinecarboxylic acid tert-butyl ester Usage And Synthesis
Uses
4-?[6-?[(8-?Cyclopentyl-?6-?ethenyl-?7,?8-?dihydro-?5-?methyl-?7-?oxopyrido[2,?3-?d]?pyrimidin-?2-?yl)?amino]?-?3-?pyridinyl]?-1-?Piperazinecarboxylic Acid 1,?1-?Dimethylethyl Ester is an impurity of Palbociclib (P139900) an experimental drug for the treatment of breast cancer being developed by Pfizer. It is a selective inhibitor of the cyclin-dependent kinases CDK4 and CDK6.
4-[6-[(8-cyclopentyl-6-ethenyl-7,8-dihydro-5-methyl-7-oxopyrido[2,3-d]pyrimidin-2-yl)amino]-3-pyridinyl]-1-piperazinecarboxylic acid tert-butyl esterSupplier
Adamas Reagent, Ltd.
- Tel
- 400-6009262 16621234537
- chenyj@titansci.com
Shanghai Kewel Chemical Co., Ltd.
- Tel
- 021-64609169 18901607656
- greensnown@163.com
Nanjing XiZe Biotechnology CO., Ltd.
- Tel
- 025-66023220 0086-15250997978
- 1511893459@qq.com
Amadis Chemical Company Limited
- Tel
- 571-89925085
- sales@amadischem.com
Shanghai XingTai Pharmaceutical Technology co., LTD
- Tel
- 15801747407
- sales01@suntechpharma.com
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4-[6-[(8-cyclopentyl-6-ethenyl-7,8-dihydro-5-methyl-7-oxopyrido[2,3-d]pyrimidin-2-yl)amino]-3-pyridinyl]-1-piperazinecarboxylic acid tert-butyl ester(1941177-45-2)Related Product Information
- Palbociclib Impurity 36
- PalBociclib Impurity 27
- Palbociclib-007
- tert-Butyl 4-(2-nitropyridin-3-yl)piperazine-1-carboxylate
- Palbociclib
- 4-[6-(6-BROMO-8-CYCLOPENTYL-5-METHYL-7-OXO-7,8-DIHYDRO-PYRIDO[2,3-D]PYRIMIDIN-2-YLAMINO)-PYRIDIN-3-YL]-PIPERAZINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER
- Palbociclib-029
- 8-cyclopentyl-5-methyl-2-((5-(piperazin-1-yl)pyridin-2-yl)amino)-6-vinylpyrido[2,3-d]pyrimidin-7(8H)-one
- Pyrido[2,3-d]pyriMidin-7(8H)-one, 8-cyclopentyl-5-Methyl-2-[[5-(1-piperazinyl)-2-pyridinyl]aMino]-
- Phosphine oxide, tris (2-methylphenyl)-
- Palbociclib-030
- tert-butyl 4-(6-((6-acetyl-8-cyclopentyl-5-methyl-7-oxo-7,8-dihydropyrido[2,3-d]pyrimidin-2-yl)amino)pyridin-3-yl)piperazine-1-carboxylate
- 1-Piperazinecarboxylic acid, 4-(2-aMino-3-pyridinyl)-, 1,1-diMethylethyl ester
- 5-(piperazin-1-yl)pyridin-2-aMine
- Palbociclib-012
- 6-broMo-2-chloro-8-cyclopentyl-5-Methylpyrido[2,3-d]pyriMidin-7(8H)-one
- PD 0332991 HCl
- 5-bromo-4-chloro-N-cyclopentylpyrimidin-2-amine