AZD5153
AZD5153 Basic information
- Product Name:
- AZD5153
- Synonyms:
-
- AZD5153
- AZD5153 (6-Hydroxy-2-naphthoic acid)
- AZD5153 (API form)
- 1869912-39-9 FREE BASE
- AZD5153 (API form)(1869912-39-9 free base)
- AZD515
- AZD 5153 6-HYDROXY-2-NAPHTHOIC ACID; AZD-5153 6-HYDROXY-2-NAPHTHOIC ACID
- AZD-5153 HNT salt
- CAS:
- 1869912-40-2
- MF:
- C36H41N7O6
- MW:
- 667.77
- Mol File:
- 1869912-40-2.mol
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AZD5153 Chemical Properties
- storage temp.
- Store at -20°C
- solubility
- DMSO:67.0(Max Conc. mg/mL);200.67(Max Conc. mM)
Ethanol:27.0(Max Conc. mg/mL);40.43(Max Conc. mM) - form
- Solid
- color
- White to off-white
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AZD5153 Usage And Synthesis
Uses
AZD5153 (6-?Hydroxy-?2-?naphthoic Acid) is a potent triazolopyridazine-based Bromodomain (BRD4) and Extraterminal (BET) inhibitor used in cancer treatments.
in vivo
Administration of AZD5153 leads to tumor stasis or regression in multiple xenograft models of acute myeloid leukemia, multiple myeloma, and diffuse large B-cell lymphoma. AZD5153 treatment markedly impacts transcriptional programs of MYC, E2F, and mTOR[1].
AZD5153Supplier
BOC Sciences
- Tel
- 1-631-485-4226; 16314854226
- info@bocsci.com
MedChemexpress LLC
- Tel
- 021-58955995
- sales@medchemexpress.cn
Shanghai Chainpharm Bio-medical Technology Co., Ltd.
- Tel
- +86-021-61727342 13611721451
- chainpharm@163.com
Shanghai Lollane Biological Technology Co.,Ltd.
- Tel
- 021-52996696,15000506266 15000506266
Shanghai Biolang biotechnology Co.,Ltd
- Tel
- 17764003753
- 2326587775@qq.com
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