ChemicalBook > Product Catalog > Biologics > Biochemical Reagents > Antagonist > Nexopamil (racemate)
Nexopamil (racemate)
Nexopamil (racemate) Basic information
- Product Name:
- Nexopamil (racemate)
- Synonyms:
-
- Nexopamil (racemate)
- 5-[N-methyl-N-(n-hexyl)]-amino-2-(3,4,5-trimethoxyphenyl)-2-isopropylvaleronitrile
- Benzeneacetonitrile, α-[3-(hexylmethylamino)propyl]-3,4,5-trimethoxy-α-(1-methylethyl)-
- CAS:
- 116759-35-4
- MF:
- C24H40N2O3
- MW:
- 404.6
- Mol File:
- 116759-35-4.mol
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Nexopamil (racemate) Chemical Properties
- Boiling point:
- 514.7±50.0 °C(Predicted)
- Density
- 0.985±0.06 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- solubility
- Soluble in DMSO
- pka
- 9?+-.0.50(Predicted)
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Nexopamil (racemate) Usage And Synthesis
Uses
Nexopamil racemate is the racemate of Nexopamil. Nexopamil is a combined Ca2+/5-HT2 antagonist on thrombus formation in vivo and on platelet aggregation in vitro.
in vivo
Nexopamil (0.05 mg/kg) completely abolishes cyclic flow reductions (CFRs) during the first 30 min after application without significantly altering hemodynamics[1].
IC 50
5-HT2 Receptor
References
[1] Kirchengast M, et al. Inhibition by the combined Ca2+ and 5-HT2 receptor antagonist nexopamil (LU 49938) of intracoronary thrombus formation in a canine model of arterial stenosis and intimal damage. J Cardiovasc Pharmacol. 1993 Nov;22(5):687-94. DOI:10.1097/00005344-199311000-00003
Nexopamil (racemate)Supplier
Fan De(Beijing) Biotechnology Co., Ltd.
- Tel
- 15911056312
- liming@bio-fount.com
TargetMol Chemicals Inc.
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- +1-781-999-5354; +17819995354
- marketing@targetmol.com
cjbscvictory
- Tel
- 13348960310
- 3003867561@qq.com
Beijing Jin Ming Biotechnology Co., Ltd.
- Tel
- 010-60605840 15801484223;
- psaitong@jm-bio.com
TargetMol Chemicals Inc.
- Tel
- 4008200310
- marketing@tsbiochem.com