Uridine, 2',3'-didehydro-2',3'-dideoxy-, 5'-acetate Chemical Properties

Melting point:

80 °C

Density 

1.370±0.06 g/cm3(Predicted)

pka

9.32±0.10(Predicted)

Uridine, 2',3'-didehydro-2',3'-dideoxy-, 5'-acetate Usage And Synthesis

Uses

5’-O-Acetyl-2’,3’-dideoxy-2’,3’-didehydro-uridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

References

[1] Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. DOI:10.2174/138161212801227005

Uridine, 2',3'-didehydro-2',3'-dideoxy-, 5'-acetate(42867-74-3)Related Product Information

• Uridine-5-oxyacetic acid methyl ester
• Uridine 5-alpha-hydroxy acetamide
• Uridine 5-oxyacetic acid
• Uridine, 2',5'-dideoxy-5'-iodo-
• Uridine, 5'-azido-5'-deoxy-2'-O-methyl-
• Uridine, 4',5'-didehydro-5'-deoxy-
• Uridine, 5-cyano-
• Uridine,4-thio-, 2',3',5'-tribenzoate (6CI,7CI,8CI,9CI)
• Uridine, 4',5'-didehydro-2',5'-dideoxy-
• Uridine,3'-azido-2',3'-dideoxy-5-hydroxy-