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Vindesine sulfate

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Vindesine sulfate Basic information

Product Name:
Vindesine sulfate
Synonyms:
  • Desacetylvinblastine amide sulfate salt
  • Fildesi
  • LY-099094
  • VINCRISITINESULFATE
  • Vincaleukoblastine, 3-(aminocarbonyl)-O4-deacetyl-3-de(methoxycarbonyl)-, sulfate (1:1) (salt)
  • VINDESINE SULFATE SALT
  • Methyl (1S,13S,15S,17S)-13-[(1R,9R,10S,11R,12R,19R)-10-carbaMoyl-12-ethyl-10,11-dihydroxy-5-Methoxy-8-Methyl-8,16-diazapentacyclo[10.6.1.0^{1,9}.0^{2,7}.0^{16,19}]nonadeca-2(7),3,5,13-tetraen-4-yl]-17-ethyl-17-hydroxy-1,11-diazatetracyclo[13.3.1.0^{4,12}.
  • Elsedine
CAS:
59917-39-4
MF:
C43H57N5O11S
MW:
852
EINECS:
261-984-7
Product Categories:
  • Anti-cancer & immunity
  • Intermediates & Fine Chemicals
  • Pharmaceuticals
  • APIs
Mol File:
59917-39-4.mol
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Vindesine sulfate Chemical Properties

Melting point:
>2500C
storage temp. 
2-8°C
solubility 
deionized water: ≥50mg/mL
form 
powder
color 
off-white to light yellow
Stability:
Hygroscopic
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Safety Information

Hazard Codes 
Xn
Risk Statements 
40
Safety Statements 
26-36
RIDADR 
1544
WGK Germany 
3
RTECS 
YY8090000
HazardClass 
6.1(a)
PackingGroup 
II
Toxicity
LD50 in mice, rats (mg/kg): 6.3 ± 0.6, 2.0 ± 0.2 i.v. (Todd); in mice: 8.8 ± 2.5 i.p. (Owellen, Biochem. Pharmacol.)
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Vindesine sulfate Usage And Synthesis

Chemical Properties

Amorphous Solid

Uses

anticancer

Uses

Vindesine Sulfate Salt is a synthetic derivative of the dimeric Catharanthus alkaloid vinblastine. Antineoplastic.

Definition

ChEBI: Vindesine sulfate is an alkaloid sulfate salt. It has a role as an antineoplastic agent. It is functionally related to a vindesine.

brand name

Eldisine (Lilly).

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