FORMANILIDE Chemical Properties

Melting point:

46-48 °C(lit.)

Boiling point:

166 °C14 mm Hg(lit.)

Density 

1.144 g/mL at 25 °C(lit.)

refractive index 

1.5908 (estimate)

Flash point:

>230 °F

storage temp. 

Sealed in dry,2-8°C

solubility 

water: soluble25.4g/L at 20°C

form 

Crystals

pka

15.00±0.70(Predicted)

Specific Gravity

1.144

color 

White to pale grayish-beige

Merck 

14,4238

BRN 

906934

Stability:

Stable. Combustible. Incompatible with strong oxidizing agents.

CAS DataBase Reference

103-70-8(CAS DataBase Reference)

EPA Substance Registry System

Formanilide (103-70-8)

Safety Information

Risk Statements 

22

Safety Statements 

22-24/25

WGK Germany 

2

RTECS 

BY1780000

F 

8

TSCA 

Yes

HS Code 

29242990

Hazardous Substances Data

103-70-8(Hazardous Substances Data)

MSDS

• Language:English Provider:ACROS
• Language:English Provider:SigmaAldrich
• Language:English Provider:ALFA

FORMANILIDE Usage And Synthesis

Chemical Properties

white or light yellow crystals or powder

Uses

Formanilide was used to study the zero electron kinetic energy(ZEKE) spectra of cis- and trans-formanilide. It was used to investigate the gas-phase structures of the two isomers of the trans-formanilide-water complex by two-colour (1+1′) resonance enhanced multiphoton ionisation (REMPI) and ZEKE spectroscopy.

Definition

ChEBI: A member of the class of formamides that is formamide in which one of the amino hydrogens is replaced by a phenyl group.

Synthesis Reference(s)

Synthetic Communications, 13, p. 635, 1983 DOI: 10.1080/00397918308060342
Tetrahedron Letters, 26, p. 3703, 1985 DOI: 10.1016/S0040-4039(00)89228-X

General Description

White crystalline solid.

Air & Water Reactions

FORMANILIDE may be sensitive to prolonged exposure to air. . Soluble in water.

Reactivity Profile

FORMANILIDE is an amide. Amides/imides react with azo and diazo compounds to generate toxic gases. Flammable gases are formed by the reaction of organic amides/imides with strong reducing agents. Amides are very weak bases (weaker than water). Imides are less basic yet and in fact react with strong bases to form salts. That is, they can react as acids. Mixing amides with dehydrating agents such as P2O5 or SOCl2 generates the corresponding nitrile. The combustion of these compounds generates mixed oxides of nitrogen (NOx).

Health Hazard

SYMPTOMS: Exposure to FORMANILIDE may cause cyanosis, headache, dizziness, confusion, decreased blood pressure, convulsions and coma.

Fire Hazard

FORMANILIDE is probably combustible.

Purification Methods

Crystallise formanilide from Et2O (m 45.3o), Et2O/pet ether (m 46o), pet ether (m 47.6o), ligroin/xylene, or distil it preferably under reduced pressure. [Beilstein 12 H 230, 12 II 135, 12 III 453.]

FORMANILIDE(103-70-8)Related Product Information

• ACID BLUE 41
• 2-Chloro-N-[4-chloro-2-(2-chlorobenzoyl)phenyl]acetamide
• 2-BENZOYLACETANILIDE
• Acetaminophen
• BENZANILIDE
• N-Acetylanthranilic acid
• 4'-Chloroacetoacetanilide
• 4-ACETAMIDOBENZONITRILE
• 3-(TRIFLUOROMETHYL)ACETANILIDE
• 2'-Fluoroacetanilide
• 4'-CHLOROACETANILIDE
• Diphenylcarbamyl chloride
• 2-Chloro-N-(2,6-dimethylphenyl)acetamide
• N-METHYL-N-PHENYLCARBAMOYL CHLORIDE
• N,N'-Diphenylurea
• 4'-Bromoacetanilide
• ACID BLUE 40
• Disperse Yellow 3