Basic information Safety Supplier Related

NORVERAPAMIL HYDROCHLORIDE

Basic information Safety Supplier Related

NORVERAPAMIL HYDROCHLORIDE Basic information

Product Name:
NORVERAPAMIL HYDROCHLORIDE
Synonyms:
  • NORVERAPAMIL HCL
  • NORVERAPAMIL HYDROCHLORIDE
  • (+/-)-VERAPAMIL, NOR-METHYL-, HYDROCHLORIDE
  • a-[3-[[2-(3,4-Dimethoxyphenyl)ethyl]amino]propyl]-3,4-dimethoxy-a-(1-methylethyl)- benzeneacetonitril
  • n-nor-(±)-verapamil hydrochloride
  • α-[3-[[2-(3,4-Dimethoxyphenyl)ethyl]amino]propyl]-3,4-dimethoxy-α-(1-methylethyl)- benzeneacetonitrile
  • (+-)-VERAPAMIL HYDROCHLORIDE, NOR-METHYL (NORVERAPAMIL HYDROCH
  • a-[3-[[2-(3,4-Dimethoxyphenyl)ethyl]amino]propyl]-3,4-dimethoxy-a-(1-methylethyl)-benzeneacetonitrile
CAS:
67812-42-4
MF:
C26H37ClN2O4
MW:
477.04
Product Categories:
  • Metabolites
  • Various Metabolites and Impurities
Mol File:
67812-42-4.mol
More
Less

NORVERAPAMIL HYDROCHLORIDE Chemical Properties

Melting point:
softens at 50°C, 155-160°C dec.
Flash point:
9℃
storage temp. 
desiccated
solubility 
H2O: >10 mg/mL
form 
solid
color 
white
Stability:
Hygroscopic
EPA Substance Registry System
Benzeneacetonitrile, .alpha.-[3-[[2-(3,4-dimethoxyphenyl)ethyl]amino]propyl]-3,4-dimethoxy-.alpha.-(1-methylethyl)-, hydrochloride (1:1) (67812-42-4)
More
Less

Safety Information

RIDADR 
UN 2811 6.1/PG 3
WGK Germany 
3

MSDS

More
Less

NORVERAPAMIL HYDROCHLORIDE Usage And Synthesis

Chemical Properties

Off-White Crystalline Solid

Uses

Nor Verapamil Hydrochloride (Verapamil EP Impurity J HCl) is a metabolite of Verapamil.

General Description

Norverapamil is a primary urinary metabolite of verapamil, a calcium channel blocker used in the treatment of hypertension, angina pectoris, and cardiac arrhythmia. Verapamil is also an effective preventive medication for migraines. This Certified Reference Material is applicable for use as starting material in calibrators or controls for verapamil testing methods by LC-MS/MS or GC-MS.

Biochem/physiol Actions

Norverapamil is an N-demethylated metabolite of verapamil. It has significantly less calcium channel blocking ability and exhibit therapeutic activity.

NORVERAPAMIL HYDROCHLORIDESupplier

Beijing Jin Ming Biotechnology Co., Ltd. Gold
Tel
010-60605840 18892239720
Email
psaitong@jm-bio.com
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Email
jkinfo@jkchemical.com
3B Pharmachem (Wuhan) International Co.,Ltd.
Tel
821-50328103-801 18930552037
Email
3bsc@sina.com
Chemsky(shanghai)International Co.,Ltd.
Tel
021-50135380
Email
shchemsky@sina.com
Acesys Pharmatech
Tel
18860950986
Email
tangmanman@zenjipharma.com