2-Hydroxybenzophenone Chemical Properties

Melting point:

37-39 °C (lit.)

Boiling point:

171-173 °C/12 mmHg (lit.)

Density 

1.1184 (rough estimate)

refractive index 

1.5954 (estimate)

Flash point:

>230 °F

storage temp. 

Sealed in dry,2-8°C

pka

8.07±0.30(Predicted)

form 

Crystalline Powder

color 

Yellow

Water Solubility 

insoluble

BRN 

1638174

CAS DataBase Reference

117-99-7(CAS DataBase Reference)

NIST Chemistry Reference

Methanone, (2-hydroxyphenyl)phenyl-(117-99-7)

EPA Substance Registry System

Methanone, (2-hydroxyphenyl)phenyl- (117-99-7)

Safety Information

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

26-37/39-36

WGK Germany 

3

TSCA 

Yes

HazardClass 

IRRITANT

HS Code 

29145000

MSDS

• Language:English Provider:2-Hydroxybenzophenone
• Language:English Provider:ACROS
• Language:English Provider:SigmaAldrich
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2-Hydroxybenzophenone Usage And Synthesis

Chemical Properties

yellow crystalline powder

Uses

UV absorber in plastics.

Uses

2-Hydroxybenzophenone was used to quantify the metabolites of unmethylated extracts from the supernatants of Pseudomonas acidovorans cultures grown on 1,1-diphenylethylene.

Application

2-Hydroxybenzophenone was used to quantify the metabolites of unmethylated extracts from the supernatants of Pseudomonas acidovorans cultures grown on 1,1-diphenylethylene.
2-Hydroxybenzophenone forms copolymer 2-hydroxy, 3-allyl, 4,4′-dimethoxybenzophenone with methyl methacrylate.
It forms photostabilizer compounds with 2,2,6,6-tetramethylpiperidine under phase transfer catalysis conditions.
It reacts with 3-aminophenyl boronic acid to form macrocyclic boronates.

Preparation

Preparation by Friedel–Crafts acylation of benzene in the presence of aluminium chloride,
? with 2-hydroxybenzoyl chloride (salicylic acid chloride), (52%), (39%), at temperature <60°;
? with o-anisoyl chloride. Demethylation occurred during the Friedel–Crafts acylation, especially in the presence of ferric chloride at 130–140°;
? with 2-ethoxybenzoyl chloride in a boiling water bath (42%).

Synthesis Reference(s)

Journal of the American Chemical Society, 76, p. 5469, 1954 DOI: 10.1021/ja01650a062
The Journal of Organic Chemistry, 32, p. 3844, 1967 DOI: 10.1021/jo01287a027

General Description

• 2-Hydroxybenzophenone forms copolymer 2-hydroxy, 3-allyl, 4,4′-dimethoxybenzophenone with methyl methacrylate.
• It forms photostabilizer compounds with 2,2,6,6-tetramethylpiperidine under phase transfer catalysis conditions.
• It reacts with 3-aminophenyl boronic acid to form macrocyclic boronates.

2-Hydroxybenzophenone(117-99-7)Related Product Information

• 2,4,4'-TRIHYDROXYBENZOPHENONE
• Alizarin
• 5-CHLORO-2-HYDROXY-4-METHYLBENZOPHENONE
• 2,2'-DIHYDROXYBENZOPHENONE
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• 1,2,5,8-TETRAHYDROXYANTHRAQUINONE
• Emodin
• 2,2'-Dihydroxy-4,4'-dimethoxybenzophenone
• PURPURIN
• 1,5-DIHYDROXYANTHRAQUINONE
• Alizarin Red S
• ACID GREEN 41
• 2,2'-Dihydroxy-4-methoxybenzophenone
• 5-Methyl-2-hydroxybenzophenone,5-Methyl-2-hydroxybenzophenone
• 2-Hydroxybenzophenone
• 2,4-Dihydroxybenzophenone
• 2,3,3',4'-TETRAMETHOXYBENZOPHENONE
• 1,4-Dihydroxyanthraquinone