Cy7 Alkyne Chemical Properties

solubility 

Soluble in DMSO, DMF, alcohols

Appearance

Dark green solid

ex/em

740/770 nm (EtOH/PBS)

ε(extinction coefficient)

199000 L⋅mol−1⋅cm−1

Φ(quantum yield)

0.3

Cy7 Alkyne Usage And Synthesis

Description

Cy7 alkyne is a Cy7 linker which can be used to react in copper-catalyzed Click Chemistry reactions with azides. It has an excitation and emission wavelength at 750/773 nm.

Chemical Properties

Appearance: Dark green solid
ex/em: 740/770 nm (EtOH/PBS)
Extinction coefficient (ε): 199000 L??mol??1??cm??1
Quantum yield (Φ): 0.3

Uses

Cy7 alkyne chloride is a dye derivative of Cyanine 7 (Cy7) containing an alkyne functional group (Ex/Em = 740/770 nm). The alkyne functionality of Cy7 alkyne chloride can react with molecules containing the azide functionality to form covalent bonds[1].

References

[1] Zhou Y, et al. Interactome analysis reveals ZNF804A, a schizophrenia risk gene, as a novel component of protein translational machinery critical for embryonic neurodevelopment. Mol Psychiatry. 2018 Apr;23(4):952-962 DOI:10.1038/mp.2017.166

Abs/Em Maxima

750/773 nm

Fluoresene quantum yield

0.3

Extinction Coefficient

199000

CF260

0.022

CF280

0.029

Spectrally Similar Dyes

Alexa Fluor® 750, RDye® 750, CF® 750 Dye, DyLight® 750

Cy7 Alkyne(1998119-13-3)Related Product Information

• diSulfo-Cy3 alkyne
• Cy5.5 alkyne
• TAMRA-PEG4-alkyne
• Sulfo-Cy7 alkyne
• 15-hexadecynoic acid
• diSulfo-Cy5 alkyne
• Cyanine7 NHS ester
• 3H-Indolium, 2-[2-[3-[2-(1,3-dihydro-1,3,3-trimethyl-2H-indol-2-ylidene)ethylidene]-1-cyclohexen-1-yl]ethenyl]-1-[6-[(2,5-dioxo-1-pyrrolidinyl)oxy]-6-oxohexyl]-3,3-dimethyl-
• Sulfo Cy7 Amine