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LOXO-195

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LOXO-195 Basic information

Product Name:
LOXO-195
Synonyms:
  • (3aR,10R)-5-Fluoro-1,2,3,3a,8,9,10,11-octahydro-10-methyl-12H-15,17-ethenopyrazolo[3,4-d]pyrido[2,3-k]pyrrolo[2,1-m][1,3,7]triazacyclotridecin-12-one
  • selitrectinib(LOXO-195)
  • CS-2800
  • LOXO-195;LOXO195
  • Selitrectinib
  • LOXO 195(Selitrectinib)
  • Selitrectinib (Synonyms: LOXO-195)
  • 12H-15,17-Ethenopyrazolo[3,4-d]pyrido[2,3-k]pyrrolo[2,1-m][1,3,7]triazacyclotridecin-12-one, 5-fluoro-1,2,3,3a,8,9,10,11-octahydro-10-methyl-, (3aR,10R)-
CAS:
2097002-61-2
MF:
C20H21FN6O
MW:
380.42
Mol File:
2097002-61-2.mol
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LOXO-195 Chemical Properties

Density 
1.51±0.1 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
DMSO:62.5(Max Conc. mg/mL);164.29(Max Conc. mM)
form 
A crystalline solid
pka
11.44±0.40(Predicted)
color 
White to yellow
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Safety Information

HS Code 
2933998090
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LOXO-195 Usage And Synthesis

Uses

LOXO-195 (Selitrectinib) is a second-generation TRK kinase inhibitor that targets TRK fusion-positive tumors and is used to treat tumor patients who are resistant to first-generation TRK inhibitors.

LOXO-195Supplier

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