Fmoc-Ile-OH Chemical Properties

Melting point:

145-147 °C(lit.)

alpha 

-12 º (c=1,DMF)

Boiling point:

486.83°C (rough estimate)

Density 

1.2107 (rough estimate)

refractive index 

-12 ° (C=1, DMF)

storage temp. 

2-8°C

solubility 

Soluble in methanol (very faint turbidity).

form 

Fine Crystalline Powder

pka

3.92±0.22(Predicted)

color 

White

optical activity

[α]20/D 12±1°, c = 1% in DMF

BRN 

4716717

InChI

InChI=1S/C21H23NO4/c1-3-13(2)19(20(23)24)22-21(25)26-12-18-16-10-6-4-8-14(16)15-9-5-7-11-17(15)18/h4-11,13,18-19H,3,12H2,1-2H3,(H,22,25)(H,23,24)/t13-,19-/m0/s1

InChIKey

QXVFEIPAZSXRGM-DJJJIMSYSA-N

SMILES

C(O)(=O)[C@H]([C@@H](C)CC)NC(OCC1C2=C(C=CC=C2)C2=C1C=CC=C2)=O

CAS DataBase Reference

71989-23-6(CAS DataBase Reference)

Safety Information

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

22-24/25-36/37/39-27-26

WGK Germany 

3

Hazard Note 

Irritant

HS Code 

2924 29 70

MSDS

• Language:English Provider:2-{[(9H-Fluoren-9-ylmethoxy)carbonyl]amino}-3-methylpentanoic acid
• Language:English Provider:SigmaAldrich
• Language:English Provider:ACROS
• Language:English Provider:ALFA

Fmoc-Ile-OH Usage And Synthesis

Description

Fmoc-Ile-OH is an isoleucine derivative. It is white fine crystalline powder and belong to Fmoc materials. Fmoc-Leu-OH forms flower-like morphology at both low and high concentration under room temperature which changes to small tube-like structure on heating^[1].

Chemical Properties

white fine crystalline powder

Uses

N-Fmoc-L-isoleucine is an unnatural amino acid used for peptidomimetics. It is also used as a pharmaceutical intermediate.

General Description

The product number for this product was previously 04-12-1024.

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References

[1] N. Gour, B. Koshti, S. Naskar, V. Kshtriya, H. Narode, Self-assembled Structures Formed by Fmoc modified aliphatic amino acids, ChemRxiv, 2021.

Fmoc-Ile-OH(71989-23-6)Related Product Information

• L-Leucine
• Fmoc-Phe-OH
• (2R,3R)-2-Amino-3-methylpentanoic acid
• 1,1'-Carbonyldiimidazole
• Fmoc-Aib-OH
• PYRAZOPHOS
• Fmoc-Asp(OtBu)-OH
• L-Isoleucine
• ALTRENOGEST
• N-CARBOBENZOXY-DL-LEUCINE
• Fmoc-Lys(Boc)-OH
• DL-Isoleucine
• L-Fmoc-Aspartic acid alpha-tert-butyl ester
• 9-Fluorenylmethyl chloroformate
• Glycine
• N-(9-Fluorenylmethoxycarbonyloxy)succinimide
• Fmoc-L-Glutamic acid gamma-methyl ester
• FMOC-L-BETA-HOMOMETHIONINE