1,1'-(Azodicarbonyl)-dipiperidine
1,1'-(Azodicarbonyl)-dipiperidine Basic information
- Product Name:
- 1,1'-(Azodicarbonyl)-dipiperidine
- Synonyms:
-
- Diphenylpiperidylcarboxylate
- AZODICARBOXYLIC ACID DIPIPERIDYL ESTER
- Azodicarboxylic
- diazenedicarboxylic acid bis(N,N-piperidide)
- 1,1-IAZODICARBONYL)DIPIPERIDINE
- Azodicarboxylic acid dipiperidine,95%
- 1,1'-(Azodicarbonyl)
- 1,1'-(Azodicarbonyl)dipiperidine(ADDP)
- CAS:
- 10465-81-3
- MF:
- C12H20N4O2
- MW:
- 252.31
- Product Categories:
-
- API intermediates
- Azodicarboxylates & Amides
- Mitsunobu Reaction
- Synthetic Organic Chemistry
- Mol File:
- 10465-81-3.mol
1,1'-(Azodicarbonyl)-dipiperidine Chemical Properties
- Melting point:
- 132-136 °C(lit.)
- Boiling point:
- 366.4±25.0 °C(Predicted)
- Density
- 1.29±0.1 g/cm3(Predicted)
- storage temp.
- Keep in dark place,Sealed in dry,Room Temperature
- solubility
- DMSO (Slightly), Methanol (Slightly), insol petroleum ether; sol ethanol, ether, THF
- pka
- -0?+-.0.20(Predicted)
- form
- solid
- color
- yellow
- Water Solubility
- Slightly soluble in water.
- BRN
- 261917
- InChI
- InChI=1S/C12H20N4O2/c17-11(15-7-3-1-4-8-15)13-14-12(18)16-9-5-2-6-10-16/h1-10H2
- InChIKey
- OQJBFFCUFALWQL-UHFFFAOYSA-N
- SMILES
- N(C(N1CCCCC1)=O)=NC(N1CCCCC1)=O
- CAS DataBase Reference
- 10465-81-3(CAS DataBase Reference)
MSDS
- Language:English Provider:SigmaAldrich
1,1'-(Azodicarbonyl)-dipiperidine Usage And Synthesis
Description
1,1''-(Azodicarbonyl)dipiperidine (ADDP) is a reagent commonly used in the Mitsunobu reaction for the condensation of an alcohol and an acidic compound. It has been used as a reagent in the synthesis of G protein-coupled receptor 120 (GPR120) agonists with antidiabetic activity and peroxisome proliferator-activated receptor α (PPARα), PPARγ, and PPARδ triple agonists.
Chemical Properties
yellow crystalline powder
Uses
It is used in a study of the copper-catalyzed addition of aryboronic acids to azodicarboxyl derivatives providing aryl-substituted hydrazides. It is widely used reagent for the Mitsunobu reaction. It is reactant for preparation of polyfluoroalkylated tripyrazolylmethane ligands, (-)-Hygromycin A via Mitsunobu glycosylation, optically active α,α-disubstituted amino acids via Mitsunobu reaction, aza-β-lactams through [2+2] cycloaddition reactions, glycosyl disulfides, pyridine ether PPAR agonists, S-glycosyl amino acid, building blocks for combinatorial neoglycopeptide synthesis and is a histamine H3 receptor antagonists. It is a reactant for Mitsunobu inversion reactions.
Reactions
1,1'-(Azodicarbonyl)-dipiperidine can selectively oxidizes a variety of alcohols to the corresponding aldehydes or ketones under basic conditions.
1,1'-(Azodicarbonyl)-dipiperidineSupplier
- Tel
- 0512-69209928 18306209922
- cathyjia@highfine.com
- Tel
- 18061915908
- 945992976@qq.com
- Tel
- +86-512-68095917 13862064516
- sales@bek.com.cn
- Tel
- 0512-68312916,63926215 18912725070
- jon@jonnmt.com
- Tel
- 021-50795510 4000665055
- sales@accelachem.com
1,1'-(Azodicarbonyl)-dipiperidine(10465-81-3)Related Product Information
- N,N,N',N'-Tetramethylazodicarboxamide
- O-Phthalimide
- Diethyl azodicarboxylate
- Dimethyl phthalate
- DIPHENYLCARBAZONE
- 2,2'-Azobis(2-methylpropionitrile)
- Azodicarbonamide
- AZODICARBOXYLIC BISMORPHOLIDE
- Dibenzyl azodicarboxylate
- Diisopropyl azodicarboxylate
- Di-tert-Butyl azodicarboxylate
- Bis(4-chlorobenzyl) azodicarboxylate
- N-Formylpiperidine
- 1,1-DIETHYLUREA
- 1-CARBAMYLPIPERIDINE
- 1,1'-(Azodicarbonyl)-dipiperidine