2-Nitrophenylacetic acid Chemical Properties

Melting point:

137-140 °C (lit.)

Boiling point:

314.24°C (rough estimate)

Density 

1.4283 (rough estimate)

refractive index 

1.5468 (estimate)

storage temp. 

Sealed in dry,Room Temperature

pka

4(at 25℃)

form 

Crystalline Powder

color 

Yellow to beige

BRN 

1959243

CAS DataBase Reference

3740-52-1(CAS DataBase Reference)

NIST Chemistry Reference

Benzeneacetic acid, 2-nitro-(3740-52-1)

EPA Substance Registry System

2-Nitrophenylacetic acid (3740-52-1)

Safety Information

Hazard Codes 

Xi,Xn

Risk Statements 

36/37/38-68

Safety Statements 

26-36-37/39

WGK Germany 

3

RTECS 

AJ1130000

TSCA 

Yes

HazardClass 

IRRITANT

HS Code 

29163900

Toxicity

mmo-sat 500 mg/plate MUREAV 170,11,86

MSDS

• Language:English Provider:2-(2-Nitrophenyl)acetic acid
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2-Nitrophenylacetic acid Usage And Synthesis

Uses

2-Nitrophenylacetic Acid is a useful research chemical.

Chemical Properties

yellow to beige crystalline powder

Uses

2-Nitrophenylacetic acid was used as an internal standard in the determination of the theophylline solubilizer salicylamide-O-acetic acid.

Definition

ChEBI: (2-nitrophenyl)acetic acid is a member of the class of phenylacetic acids that is phenylacetic acid in which the phenyl grup is substituted at the ortho- position by a nitro group. It is a C-nitro compound and a member of phenylacetic acids. It is functionally related to a nitrobenzene and a phenylacetic acid.

Safety Profile

Mutation data reported. Forms an explosive mixture with thionyl chloride. When heated to decomposition it emits toxic fumes of NOx.

Purification Methods

The acid crystallises as yellow needles from EtOH, EtOH/water and dry it over P2O5 under vacuum. The amide has m 160-161o (from *C6H6 plates or EtOH, needles). [Beilstein 9 III 2282, 9 IV 1687.]

2-Nitrophenylacetic acid(3740-52-1)Related Product Information

• Folic acid
• 2-Hydroxyphenylacetic acid
• DL-Mandelic acid
• Glycine
• Sodium 3-nitrobenzenesulphonate
• 4-Nitrobenzoic acid
• 4-Nitrobenzaldehyde
• 4-Methoxyphenylacetic acid
• Ethyl 2-(Chlorosulfonyl)acetate
• Ethyl acetate
• 4-Hydroxyphenylacetic acid
• 2-Nitrobenzyl alcohol
• Sodium 2-nitrophenoxide
• 2-Nitrodiphenylamine
• 2-Nitrobenzaldehyde
• 2-Nitrobenzyl bromide
• 2-Nitrobenzoic acid
• Phenylacetic acid