8-HYDROXYGUANINE CAS#: 5614-64-2

8-HYDROXYGUANINE Basic information

Product Name:

8-HYDROXYGUANINE

Synonyms:

7,8-DIHYDRO-8-OXOGUANINE
8-OXOGUANINE
8-OXOG
8-HYDROXYGUANINE
2-Amino-1,6,7,8-tetrahydro-9H-purine-6,8-dione
2-Amino-6-hydroxy-7H-purin-8(9H)-one
2-Amino-8-hydroxy-9H-purine-6(1H)-one
8-Oxodihydroguanine

CAS:

5614-64-2

MF:

C5H5N5O2

MW:

167.13

EINECS:

227-035-6

Product Categories:

Miscellaneous Biochemicals
Pyridines, Pyrimidines, Purines and Pteredines
Nucleotides and Nucleosides
Bases & Related Reagents
Nucleotides
Amines
Heterocycles

Mol File:

5614-64-2.mol

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8-HYDROXYGUANINE Chemical Properties

Melting point:: >400°C dec.
Density: 2.52±0.1 g/cm3(Predicted)
storage temp.: Store at -20°C
solubility: Water: < 0.1 mg/mL (insoluble); Ethanol: < 1 mg/mL (insoluble); DMSO: < 1 mg/mL (insoluble or slightly soluble)
form: Solid
pka: 8.73±0.20(Predicted)
color: Light brown to khaki

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Safety Information

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26-36

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8-HYDROXYGUANINE Usage And Synthesis

Chemical Properties

White Powder

Uses

Involved in DNA lesion repair.

Uses

2-Amino-6,8-dihydroxypurine is an 8-oxo-guanine repair pathway coordinated by MUTYH glycosylase and DNA polymerase λ.

Definition

ChEBI: An oxopurine that is guanine in which the hydrogen at position 8 is replaced by an oxo group and in which the nitrogens at positions 7 and 9 each bear a hydrogen.

8-HYDROXYGUANINESupplier

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