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2-Aminothiazole-4-acetic acid

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2-Aminothiazole-4-acetic acid Basic information

Product Name:
2-Aminothiazole-4-acetic acid
Synonyms:
  • (2-AMino-1,3-thiazol-4-yl)acetic acid
  • 2-AMino-4-thiazolacetic acid
  • Ceftibuten Related Impurity 2
  • 2-(2-amino-1,3-thiazol-4-yl)ethanoic acid
  • Ethyl-2-(2-aminothiazol-4-yl)-2-oxo-acetate(EAOA)
  • 2-Aminothiazol-4-acetic aCld
  • ATAH 2-(2-Aminothiazol-4-yl) acetic acid
  • 2-(2-azaniumyl-1,3-thiazol-4-yl)acetate
CAS:
29676-71-9
MF:
C5H6N2O2S
MW:
158.18
EINECS:
249-769-6
Product Categories:
  • Building Blocks
  • Heterocyclic Building Blocks
  • Organic acids
  • (intermediate of cefotiam)
  • Cephalosporins
  • Thiazoles
  • Nitrogen cyclic compounds
  • Sulphur Derivatives
  • Heterocyclic Compounds
  • 29676-71-9
Mol File:
29676-71-9.mol
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2-Aminothiazole-4-acetic acid Chemical Properties

Melting point:
130 °C (dec.)(lit.)
Boiling point:
399.0±17.0 °C(Predicted)
Density 
1.367 (estimate)
vapor pressure 
1.03-1.15hPa at 20℃
refractive index 
1.6430 (estimate)
storage temp. 
-20°C
solubility 
DMSO (Slightly)
pka
3.20±0.10(Predicted)
form 
solid
color 
White
Water Solubility 
6.5 g/L (20 ºC)
BRN 
127415
Stability:
Unstable in Solution
LogP
-2.13 at 20℃ and pH4.54-4.64
CAS DataBase Reference
29676-71-9(CAS DataBase Reference)
EPA Substance Registry System
2-Amino-4-thiazoleacetic acid (29676-71-9)
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Safety Information

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-37/39
WGK Germany 
3
HS Code 
29349990

MSDS

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2-Aminothiazole-4-acetic acid Usage And Synthesis

Chemical Properties

Almost white to light beige crystalline powder

Uses

2-Amino-4-thiazoleacetic acid has been used in:

  • preparation of poly(2-amino-4-thiazoleacetic acid)/multiwalled carbon nanotubes modified glassy carbon electrodes, for the voltammetric determination of copper ions
  • electrochemical synthesis of novel thiozole-based copolymer with 2-aminothiazole
  • preparation of aquabis(2-amino-1,3-thiazole-4-acetato-κ2O,N3)nickel (II)

General Description

Light orange powder.

Air & Water Reactions

Insoluble in water.

Reactivity Profile

An organosulfide and amine derivative, carboxylic acid. Look at Reactive Groups 20 (organosulfides), 7 (amines), and 3 (carboxylic acids) may give indications about reactive tendencies.

Fire Hazard

Flash point data for 2-Aminothiazol-4-acetic acid are not available. 2-Aminothiazol-4-acetic acid is probably combustible.

2-Aminothiazole-4-acetic acid Preparation Products And Raw materials

Preparation Products

7-(((2-Amino-4-thiazolyl)(methoxyimino)acetyl)amino)-3-(((5-(carboxymethyl)-4-methyl-2-thiazolyl)thio)methyl)-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid2-Amino-((1-carboxy-1-methyl ethoxy)imino)-4-thiazoleacetic acid

Raw materials

Thiocarbamide

2-Aminothiazole-4-acetic acidSupplier

Taizhou Huaxi Technology Co. LTD Gold
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0576-89164227 13105618688
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Anhui Dexinjia Biopharm Co., Ltd Gold
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0531-82375878 15269101859
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Zhejiang Chenxi Technology Co., LTD Gold
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13552015630
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Zhejiang Huafang Pharmaceutical Co., Ltd Gold
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0576-84169890 13857636664
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xck@huafangpharm.com
Shandong Jincheng Pharmaceutical Group Co.,Ltd. Gold
Tel
0533-5439427 13964385406;
Email
henry.zhang@jinchengpharm.com
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