Ligustilide
Ligustilide Basic information
- Product Name:
- Ligustilide
- Synonyms:
-
- Z-LIGUSTILIDE
- 1(3H)-Isobenzofuranone,3-butylidene-4,5-dihydro-
- (3Z)-3-Butylidene-4,5-dihydroisobenzofuran-1(3H)-one
- 3-[(Z)-Butylidene]-1,3,4,5-tetrahydroisobenzofuran-1-one
- 3-[(Z)-Butylidene]-4,5-dihydrophthalide
- 3-Butylidene-4,5-dihydroisobenzofuran-1(3H)-one
- Angelica Extract Powder
- 3-BUTYLIDEN-4,5-DIHYDRO-3H-ISOBENZOFURAN-1-ONE
- CAS:
- 4431-01-0
- MF:
- C12H14O2
- MW:
- 190.24
- Product Categories:
-
- chemical reagent
- pharmaceutical intermediate
- phytochemical
- reference standards from Chinese medicinal herbs (TCM).
- standardized herbal extract
- Mol File:
- 4431-01-0.mol
Ligustilide Chemical Properties
- Boiling point:
- 377.9±11.0 °C(Predicted)
- Density
- 1.10±0.1 g/cm3(Predicted)
- storage temp.
- -20°C, protect from light, stored under nitrogen
- solubility
- DMSO : 100 mg/mL (525.65 mM; Need ultrasonic)
- form
- Oil
- Stability:
- Light Sensitive
- LogP
- 1.710 (est)
Ligustilide Usage And Synthesis
Uses
Ligustilide, is a dihydrophthalide, and an active ingredients of umbelliferous plants as Angelica sinensis and Ligusticum chuanxiong, having wide range of pharmacology effects on neuroprotection, vasodilatation, anti-caner and anti-tumor, analgesia and anti-inflammation.
Definition
ChEBI: A natural product found in Ligusticum porteri.
Biological Activity
Ligustilide can inhibit the proliferation of and cell cycle progression of vascular smooth muscle cells and inhibits vasoconstriction. It increases vasodilation, anti-thrombosis, and serotonergic activity and decreases platelet aggregation. It has been shown to have broad applications in the study and treatment of cardiovascular diseases and ischemic brain injury. Ligustilide has the ability to reduce neurogenic and inflammatory pain. Thus, it can be used as a potential therapeutic agent to tre at several pain syndromes including primary dysmenorrhoea.
LigustilideSupplier
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Ligustilide(4431-01-0)Related Product Information
- Tetrahydrofuran
- D-(+)-Glucono-1,5-lactone
- Spironolactone
- D-Glucurone
- 2,3-Dihydrobenzofuran
- Furazolidone
- ε-Caprolactone
- Anelicae(Dong Quai)P.E. ligustilide 1% HPLC,Anelicae(Dong Quai)P.E. ligustilide 1% HPLC
- LIGUSTILIDE, Z-(AHP),LIGUSTILIDE, Z-(AHP)
- LIGUSTILIDE, Z-,Z-LIGUSTILIDE,LIGUSTILIDE, Z-,Z-LIGUSTILIDE
- Methyl vinyl ketone
- POLY(TETRAHYDROFURAN) STANDARD 15000
- Ligustilides
- Ligustilide
- LIGUSTILIDE, Z-(IN DMSO)(P),LIGUSTILIDE, Z-(IN DMSO)(P)
- DONG QUAI 1% LIGUSTILIDE,DONG QUAI 1% LIGUSTILIDE
- ANGELICA SINESIS EXRACT/ FERULIC ACID LIGUSTILIDE,ANGELICA SINESIS EXRACT/ FERULIC ACID LIGUSTILIDE
- ANGELICA P. E./ LIGUSTILIDE,ANGELICA P. E./ LIGUSTILIDE