4-Methoxypyridine Chemical Properties

Melting point:

4 °C

Boiling point:

108-111 °C/65 mmHg (lit.)

Density 

1.075 g/mL at 25 °C (lit.)

refractive index 

1.518-1.522

Flash point:

74 °C

storage temp. 

Keep in dark place,Sealed in dry,Room Temperature

solubility 

DMSO (Slightly), Methanol (Slightly)

form 

Liquid

pka

6.58(at 25℃)

Specific Gravity

1.075

color 

Clear colorless to slightly yellow

BRN 

108211

CAS DataBase Reference

620-08-6(CAS DataBase Reference)

NIST Chemistry Reference

Pyridine, 4-methoxy-(620-08-6)

Safety Information

Hazard Codes 

Xn,Xi

Risk Statements 

36/37/38-20/21/22

Safety Statements 

37/39-26-36-36/37/39

WGK Germany 

3

HS Code 

29339900

MSDS

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4-Methoxypyridine Usage And Synthesis

Chemical Properties

clear colorless to slightly yellow liquid

Uses

4-Methoxypyridine, is used as a building block for the synthesis of some biologically active compounds. It is used for the preparation of a new series of benzoylated N-ylides as protein farnesyltransferase inhibitors.

Uses

4-Methoxypyridine was used as a starting reagent for the stereocontrolled synthesis of (±)-pumiliotoxin C and (±)-lasubine II. It was also used in an efficient construction of dihyropyridin-4-ones, which serves as potential ligands for neuronal nicotinic acetycholine receptors.

General Description

4-Methoxypyridine has been prepared from 4-methoxypyridine-N-oxide, via catalytic hydrogenation. Ortho lithiation of 4-methoxypyridine using mesityllithium as the metalating base has been studied.

4-Methoxypyridine(620-08-6)Related Product Information

• 4-Methoxyphenylacetic acid
• 4-Methoxyphenylacetone
• 4-Methylpyridine
• Anisole
• 3-(METHOXYMETHOXY)BENZALDEHYDE
• (Trifluoromethoxy)benzene
• 4-Methoxybenzylchloride
• p-Anisaldehyde
• p-Anisidine
• 4-METHOXY-2-QUINOLINECARBOXYLIC ACID
• 4-METHOXYPYRIDINE-N-OXIDE HYDRATE, 99
• 4-Methoxy-3-nitropyridine
• 4-(Benzyloxy)pyridine N-oxide
• Esomeprazole
• 4-METHOXY-3-NITROPYRIDINE HYDROCHLORIDE
• p-methoxypyridine n-oxide
• 5-FLUORO-4-IODO-2-METHOXYPYRIDINE
• 2-Methoxypyridine