DESMETHYLXANTHOHUMOL Chemical Properties

Melting point:

154-155 °C

Boiling point:

570.7±50.0 °C(Predicted)

Density 

1.312±0.06 g/cm3(Predicted)

solubility 

Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.

form 

powder

pka

7.35±0.50(Predicted)

color 

Yellow

DESMETHYLXANTHOHUMOL Usage And Synthesis

Uses

Desmethylxanthohumol is a prenylated hydroxychalcone isolated from hop cones (Humulus lupulus L.). Desmethylxanthohumol is a powerful apoptosis inducing agent. Desmethylxanthohumol has antiplasmodial, antiproliferative, and antioxidant bioactivities[1][2].

Definition

ChEBI: A member of the class of chalcones that is trans-chalcone substituted by hydroxy groups at positions 4, 2', 4', and 6' and a 3-methylbut-2-en-1-yl group at position 3' respectively.

References

[1] Yuou Teng, et al. Synthesis and Antioxidant Evaluation of Desmethylxanthohumol Analogs and Their Dimers. Eur J Med Chem. 2017 Jan 5;125:335-345. DOI:10.1016/j.ejmech.2016.09.024
[2] Reinhard A.Diller, et al. 71-Desmethylxanthohumol from Hops, Chemistry and Biological Effects. Beer in Health and Disease Prevention, 2009, Pages 703-709.

DESMETHYLXANTHOHUMOL(115063-39-3)Related Product Information

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