Nonaethylene Glycol Monomethyl Ether Chemical Properties

Melting point:

14 °C

Boiling point:

170 °C(Press: 0.01 Torr)

Density 

1.10

refractive index 

1.4570 to 1.4620

pka

14.36±0.10(Predicted)

form 

clear liquid

color 

Colorless to Light yellow to Light orange

InChI

InChI=1S/C19H40O10/c1-21-4-5-23-8-9-25-12-13-27-16-17-29-19-18-28-15-14-26-11-10-24-7-6-22-3-2-20/h20H,2-19H2,1H3

InChIKey

VVHAVLIDQNWEKF-UHFFFAOYSA-N

SMILES

C(O)COCCOCCOCCOCCOCCOCCOCCOCCOC

Safety Information

HS Code 

2909.49.6000

Nonaethylene Glycol Monomethyl Ether Usage And Synthesis

Description

m-PEG9-alcohol is a PEG linker containing a hydroxyl group. The hydroxyl group enables further derivatization or replacement with other reactive functional groups. The hydrophilic PEG spacer increases solubility in aqueous media.

Definition

ChEBI: Nonaethylene glycol monomethyl ether is nonaethylene glycol in which one of the hydroxy groups is substituted by methoxy. It is functionally related to a nonaethylene glycol.

in vitro

Nonaethylene glycol monomethyl ether is a PEG-based PROTAC linker that can be used to synthesize PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase, and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

Nonaethylene Glycol Monomethyl Ether (6048-68-6)Related Product Information

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