1,5-Dimethylhexylamine Chemical Properties

Melting point:

25°C

Boiling point:

154-156 °C(lit.)

Density 

0.767 g/mL at 25 °C(lit.)

refractive index 

n20/D 1.422(lit.)

Flash point:

120 °F

storage temp. 

Flammables area

solubility 

DMSO (Slightly), Methanol (Slightly)

form 

Liquid

pka

pKa 10.28 ± 0.1(H2O,t =25±0.2,I<0.001) (Uncertain)

color 

White to Off-White

Merck 

14,6757

BRN 

1209250

Stability:

Hygroscopic

CAS DataBase Reference

543-82-8(CAS DataBase Reference)

NIST Chemistry Reference

Octodrine(543-82-8)

EPA Substance Registry System

2-Heptanamine, 6-methyl- (543-82-8)

Safety Information

Hazard Codes 

Xn

Risk Statements 

10-22-36/37/38

Safety Statements 

26-36/37/39-37/39-16

RIDADR 

UN 1993 3/PG 3

WGK Germany 

3

RTECS 

MQ4840000

F 

10-34

TSCA 

Yes

HazardClass 

3

PackingGroup 

III

MSDS

• Language:English Provider:SigmaAldrich
• Language:English Provider:ACROS
• Language:English Provider:ALFA

1,5-Dimethylhexylamine Usage And Synthesis

Chemical Properties

clear colorless to light yellow liquid with fishy smell.

Uses

1,5-Dimethylhexylamine is an aliphatic secondary amine which shows leucine aminotransferase inhibition. 1,5-Dimethylhexylamine is used in the preparation of glycosyl β-amino acids with antitubercular activity.

Uses

2-Amino-6-methylheptane can be used as:

• A building block for the synthesis of n-type photoconductor, N,N′-bis(1,5-dimethylhexyl)-3,4:9,10-perylenebis (dicarbox-imide) (PDHEP).
• A reagent in the synthesis of substituted pyrrolidones by reductive amination of levulinic acid using supported platinum catalyst.
• A nucleophilic amine in the synthesis of unsymmetrical sulfamide by reacting with sulfamic acid salts and triphenylphosphine ditriflate.

Application

1,5-Dimethylhexylamine can be used as a local anesthetic and vasoconstrictor, and it is mainly used as an intermediate in the production of gastrointestinal antispasmodic drug octamylamine.

Preparation

1,5-Dimethylhexylamine was synthesized from 6-methyl-2-heptanone ([928-68-7]) by amination and catalytic hydrogenation.

Definition

ChEBI: Octodrine is an alkylamine.

1,5-Dimethylhexylamine(543-82-8)Related Product Information

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